FY25 sbir phase III - nvasive: unraveling the enigma of metastasis

Active Definitive Contract Awarded Last action

Contract number
80NSSC25CA074
Awardee
Awarding agency
Obligated
$4,477,527

Award facts

Contract value 86% obligated
$5,217,527.00 Current and potential, with all options
Completion date 48% complete
Current and potential, with all options
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources · 500 offers Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Farmington, CT 06032, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00005 $3,247,527
Additional Work (new agreement, FAR part 6 applies) P00003 $300,000
Other Administrative Action P00002 · FY25 sbir phase III - nvasive: unraveling the enigma $0
Funding Only Action P00001 $440,000
Original award $490,000

About this award

The NASA Shared Services Center awarded a $5,217,527 definitive contract to Encapsulate Inc. for FY25 SBIR Phase III development under the NVASIVE project on May 23, 2025, under a total small business set-aside.

Encapsulate Inc. is a self-certified small disadvantaged business based in Farmington, Connecticut. The contract is firm fixed price with an ultimate completion date of May 22, 2028. Work is performed at Encapsulate Inc.'s Farmington, CT facility.

The originating solicitation funds NVASIVE: Unraveling the Enigma of Metastasis, which applies artificial intelligence and machine learning to predict metastasis using noninvasive techniques and microgravity research environments. The project develops automated microfluidic biochip platforms integrated with bioreactors and 3D tumor models designed to test patient-derived cancer cells against chemotherapy drugs, enabling personalized treatment selection prior to therapy initiation. The technology targets colorectal and pancreatic cancers, addressing the challenge that over 70 percent of cancer patients undergo ineffective chemotherapy through trial-and-error methods.

This Phase III award follows Encapsulate's Phase I contract ($156,494, completed February 6, 2025) and Phase II contract ($899,787, scheduled completion July 15, 2027), all designated as total small business set-asides under the SBIR program.

Quick answers

Who was awarded contract 80NSSC25CA074?

80NSSC25CA074 was awarded to Encapsulate Inc. by Shared Services Center (National Aeronautics and Space Administration) on May 23, 2025.

How much is contract 80NSSC25CA074 worth?

The government has obligated $4,477,527 on 80NSSC25CA074. Its current value, with exercised options, is $5,217,527.

Was contract 80NSSC25CA074 competed?

The extent of competition for 80NSSC25CA074 was full and open competition after exclusion of sources. The government received 500 offers. It was set aside: Total Small Business.

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