Phase II sbir - 80NSSC25C0036 nvasive: an AI and machine learning approach for metastasis prediction using nvasive and microgravity

Active Definitive Contract Awarded Last action

Contract number
80NSSC25C0036
Awardee
Awarding agency
Obligated
$899,787

Award facts

Contract value 100% obligated
$899,787.00 Current and potential, with all options
Completion date 65% complete
Current and potential, with all options
Contracting staff
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources · 500 offers Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Farmington, CT 06032, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00001 $0
Original award $899,787

About this award

Encapsulate Inc., a Farmington, Connecticut-based small disadvantaged business, has been awarded an $899,787 Phase II Small Business Innovation Research (SBIR) contract by the NASA Shared Services Center. The definitive contract, designated as a total small business set-aside with firm fixed pricing, extends through July 15, 2027. Under the NVASIVE project, Encapsulate Inc. will advance artificial intelligence and machine learning methodologies to predict cancer metastasis using noninvasive techniques and microgravity research environments. The Phase II effort builds on the company's Phase I contract (valued at $156,494 and completed in early 2025) and represents continued federal investment in the company's precision oncology platform.

The contract supports the development of automated microfluidic biochip platforms integrated with bioreactors and 3D tumor models, enabling patient-specific drug response prediction for cancer treatment applications. The work will be performed at Encapsulate's Farmington facility and focuses on creating scalable diagnostic technologies that test patient-derived cancer cells against chemotherapy drugs to enable personalized treatment selection prior to therapy initiation. This Phase II award is part of a broader federal investment in Encapsulate Inc. exceeding $5.3 million, including complementary funding from the National Science Foundation, validating the company's approach to addressing the estimated $2 billion domestic market opportunity in colorectal and pancreatic cancer treatment.

Quick answers

Who was awarded contract 80NSSC25C0036?

80NSSC25C0036 was awarded to Encapsulate Inc. by Shared Services Center (National Aeronautics and Space Administration) on July 16, 2025.

How much is contract 80NSSC25C0036 worth?

The government has obligated $899,787 on 80NSSC25C0036.

Was contract 80NSSC25C0036 competed?

The extent of competition for 80NSSC25C0036 was full and open competition after exclusion of sources. The government received 500 offers. It was set aside: Total Small Business.

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