Development of UM-1098: a novel synthetic TH17 inducing adjuvant and delivery system
Active Definitive Contract Awarded Last action
- Contract number
- 75N93023C00047
- Awardee
-
University Of Montana UEI DAY7Z8ZD48Q3
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $12,859,404
Award facts
- Opportunity
-
- 75N93022R00009 Solicitation number
- Contract value 100% obligated
- $12,859,404.00 Current and potential, with all options
- Completion date 62% complete
-
- Current, with exercised options
- Potential, with all options
- NAICS code
- 541512 Computer Systems Design Services
- Set-aside
- No set-aside
- Competition
- Full and Open Competition · 24 offers Negotiated Proposal / Quote
- Pricing
- Firm Fixed Price
- Place of performance
- Missoula, MT 59812, USA
- Legislative mandates
-
- Employment Eligibility Verification (E-Verify) FAR subpart 22.18
- Service Contract Inventory FAR subpart 4.17
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Exercise an Option | $3,293,198 | |
| Change Order | $1,641,451 | |
| Other Administrative Action | $0 | |
| Change Order | $3,504,851 | |
| Exercise an Option | $2,000,000 | |
| Original award | $2,419,904 |
About this award
The National Institute of Allergy and Infectious Diseases awarded a definitive contract to University of Montana for development of UM-1098, a novel synthetic TH17-inducing adjuvant and delivery system, on September 30, 2023, with a ceiling value of $12.859 million and ultimate completion date of September 29, 2028.
Place of performance is Missoula, Montana. The contract is firm fixed price with no set-aside designation.
The originating solicitation calls for development of a vaccine adjuvant candidate, including scale-up and process development on a 50-gram scale, analytical assay development for active pharmaceutical ingredient and final product release, product release specifications and manufacturing batch record preparation, pre-cGMP formulation lot preparation sufficient for non-clinical IND-enabling studies, and oversight of non-GLP toxicology and pharmacokinetic/ADME studies. Subcontractors include Montana State University (adjuvant production and analytical support), Inimmune Corp (scale-up, process development, and formulation activities), The University of Chicago (in vitro, ex vivo, and in vivo evaluation of optimized formulations in mice and non-human primates), Icahn School of Medicine at Mount Sinai (H5N1 and H5N2 subunit vaccine development), and West Virginia University Research Corporation (SARS-CoV-2 vaccine evaluation).
Service Contract Inventory reporting shows FY2025 invoicing of $2.4 million across 1.6 FTEs and 3,305 contractor hours, with a derived government-paid hourly rate of $738.20/hr. Subcontractors accounted for 54% of contractor hours in FY2025. FY2024 reported $1.2 million invoiced across 92 contractor hours at a blended rate of $13,481.17/hr reflecting minimal labor footprint early in performance.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Montana State University | $132,500 | |
| Inimmune Corp | $233,377 | |
| The University Of Chicago | $549,775 | |
| Inimmune Corp | $80,651 | |
| Icahn School Of Medicine At Mount Sinai | $575,022 | |
| West Virginia University Research Corporation | $415,626 | |
| Inimmune Corp | $649,639 | |
| Inimmune Corp | $63,890 | |
| The University Of Chicago | $566,369 |
Quick answers
Who was awarded contract 75N93023C00047?
75N93023C00047 was awarded to University Of Montana by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 30, 2023.
How much is contract 75N93023C00047 worth?
The government has obligated $12,859,404 on 75N93023C00047.
Was contract 75N93023C00047 competed?
The extent of competition for 75N93023C00047 was full and open competition. The government received 24 offers.
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