Characterizing and improving humanized immune system mouse models (IMM-his)

Ended Definitive Contract Awarded Last action

Contract number
75N93021C00004
Awardee
Awarding agency
Obligated
$2,463,733

Award facts

Opportunity
Contract value 100% obligated
$2,463,733.16 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 5 offers Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Madison, WI 53715, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00007 -$380
Other Administrative Action P00006 $0
Other Administrative Action P00005 $0
Funding Only Action P00004 $387,500
Other Administrative Action P00003 $0
Other Administrative Action P00002 $0
Other Administrative Action P00001 $0
Original award $2,076,613

About this award

Written by GovTribe AI ·

The National Institute of Allergy and Infectious Diseases awarded a definitive contract to University Of Wisconsin System (through University of Wisconsin - Madison) for characterizing and improving humanized immune system mouse models on February 2, 2021, with a ceiling value of $2,463,733.16 under cost-no-fee pricing and no set-aside.

The originating solicitation, posted as a Special Notice and Broad Agency Announcement in January 2019, sought proposals for developing radiation and nuclear medical countermeasures to treat tissue injuries from ionizing radiation exposure in radiological or nuclear incidents. The BAA offered up to $4 million per year for one to two awards. This contract focuses on pluripotent stem cell-derived thymic epithelial cells (PSC-TE) and induced pluripotent stem cell technical research to evaluate regenerative medicine therapy protocols through comparative studies with primary thymus tissue and transplantation experiments in immune-deficient mouse strains.

Place of performance is Madison, WI. The ultimate completion date is August 30, 2025.

Subcontractors include the University of Calgary (iPSC-TEP production and inventory development) and The Morgridge Institute For Research, Inc. (single-cell RNA sequencing analysis and study design).

Service Contract Inventory reporting shows declining labor trajectory. FY2025 invoiced $9 thousand at 0.5 FTEs and 978 contractor hours, with 92 percent of hours subcontracted out and a derived government-paid rate of $9.41/hr. The contract peaked in FY2022 at $160 thousand invoiced across 3.3 FTEs and 6,795 hours at $23.49/hr, declining steadily through contract completion.

Subawards

Subcontractor Amount Awarded
The Governors Of The University Of Calgary CHARACTERIZING AND IMPROVING HUMANIZED IMMUNE SYSTEM MOUSE MODELS (IMM-HIS) The Chu Lab at U Calgary will produce an inventory of iPSC-TEP from n=4… $37,755
The Morgridge Institute For Research, Inc. CHARACTERIZING AND IMPROVING HUMANIZED IMMUNE SYSTEM MOUSE MODELS (IMM-HIS) This project will create a regenerative medicine therapy; pluripotent stem… $49,434

Quick answers

Who was awarded contract 75N93021C00004?

75N93021C00004 was awarded to University Of Wisconsin System by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on February 2, 2021.

How much is contract 75N93021C00004 worth?

The government has obligated $2,463,733 on 75N93021C00004.

Was contract 75N93021C00004 competed?

The extent of competition for 75N93021C00004 was full and open competition. The government received 5 offers.

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