Project Grant R61NS133274

Award Date 9/1/24
Completion Date 8/31/25
Dollars Obligated $455K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90095, USA
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  1. Quantifying comprehensive neurovascular and behavioral responses to established migraine triggers and cortical spreading depression using the microchip/video recording system.
  2. Characterizing the effects of acute migraine therapies on the response to migraine triggers and cortical spreading depression to validate the platform as a tool for discovering and characterizing new acute migraine treatments.
  3. Characterizing the effects of migraine preventive therapies using the microchip/video platform.

The platform will be validated through independent replication of key findings at two different institutions. The University of California, Los Angeles (UCLA) is the primary awardee, and they have subcontracted work to the Washington University in St. Louis to assist in establishing and validating the microchip recording-triggering system.

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