The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $187,831 Project Grant (CFDA #93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to the University of California, Davis to develop a miniature two-photon microscope that can simultaneously perform high-resolution calcium imaging and optogenetic manipulation of neural activity in freely-behaving mice. The project will integrate innovative beam forming techniques into a...
The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
This $556,525 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program is funding the development, testing, and dissemination of advanced micro-LED optoelectrode platforms. The award recipient, the Regents of the University of Michigan, will design and optimize high-density micro-LED optoelectrodes in various configurations to enable...
This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), will support the development of a Light Pipe Microscope (LPM) system. The $681,287 award, effective from August 1, 2024 to July 31, 2027, will enable researchers at Purdue University and the University of California, San Diego to create an LPM system...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $374,399 in funding to the University of California, Davis to develop innovative two-photon microscopy systems with scattering correction capabilities for deep tissue imaging. The goal of this research is to enable high-speed, high-resolution imaging through scattering biological tissues, such as intact mouse organs, by...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $314,113 to Physical Sciences Inc. (PSI) to develop and demonstrate a high-speed, multicolor confocal fluorescence imager. The goal is to enable simultaneous capture of multi-wavelength signals and display them as separated or merged multicolor images and 3-D stacks. This technology will be used to map complex neuronal network activity...
This federal Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), is providing $361,992 to The Regents of the University of California, Berkeley (UC Berkeley) over a 4-year period from September 1, 2024 to August 31, 2028. The primary goals of this project are to further optimize UC Berkeley's Free-space...
This federal Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $942,983 to acquire a Bruker Luxendo TruLive3D light-sheet microscope system. The award, effective September 1, 2024 through August 31, 2025, will enable rapid 3D volumetric imaging of live specimens such as mouse, fly, and zebrafish embryos with high resolution and minimal phototoxicity. This advanced microscope system will benefit a user group of...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $293,588 Project Grant (CFDA 93.853) to Iris Kinetics Inc. in Boston, MA to develop a new multi-spectral light source called the "Effective Uniform Color-Light Integration Device (EUCLID)". The objective is to create a compact, controllable, and highly uniform illumination system to enable improved multi-spectral biological imaging applications, with a focus on mesoscale brain imaging to monitor neuronal...