APPENDIX B_Solution Summary Format and Instructions_IGoR.docx

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Attached to
Intelligent Generator of Research (IGoR) - ISO
Solicitation number
ARPA-H-SOL-26-155
Issued by

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This file is an appendix containing the Solution Summary format and submission instructions for the Intelligent Generator of Research (IGoR) program solicitation (ARPA-H-SOL-26-155) issued by the National Institutes of Health under the Department of Health and Human Services. The Solution Summary serves as the initial proposal submission document for this ARPA-H solicitation.

The submission must include organizational information (prime and sub-awardee details), estimated project duration, animal and human subject declarations, total funding requested from ARPA-H, and places of performance. Proposers must structure their submissions in six sections: (1) Concept Summary (minimal jargon explanation addressing ISO interest areas), (2) Innovation and Impact (identifying sought outcomes, disruptive potential, and quantitative metrics comparing proposed solutions to existing technologies), (3) Proposed Work (final deliverables, interim milestones, technical approach, alternative approaches considered, supporting data, adoption challenges, and technical risks), and (4) Team Organization and Capabilities (roles, responsibilities, and qualifications of key personnel). Sections 1-4 are collectively limited to 8 pages, formatted for 8.5 by 11-inch paper with 1-inch margins and sans serif font no smaller than 11 point (8-10 point acceptable for figures and tables). Additional required sections not subject to page limits include Basis of Estimate (BOE) covering all costs and resource sharing details and References Cited with bibliographic information and persistent identifiers. All submissions must be in PDF, ODX, DOC, or DOCX format, written in English, with solutions due by the date specified in the ISO Summary Information Section.

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APPENDIX B: SOLUTIONS SUMMARY FORMAT AND INSTRUCTIONS

<PRIME ORGANIZATION LOGO (optional)>

Innovative Solutions Opening Title

Solution Summary Title

Prime Organization Name

Prime Organization Type
Choose all that apply:

☐ For-Profit ☐ Non-profit ☐ Academia

SAM.gov Universal Entity Identifier (UEI) (If already registered, not required at Solution Summary stage)

Contact Address - State

Key Personnel/Staff
Name:

Email:

Organization:

(Repeat, as necessary)

Prime Technical Point of Contact (POC)
Name:

Mailing Address:

Telephone:

Email:

Prime Administrative POC
Name:

Mailing Address:

Telephone:

Email:

Estimated Project Duration
____ Months
Animal Subjects
☐ Yes ☐ No
Human Subjects
☐ Yes ☐ No
Total Funds Requested From ARPA-H (including all phases)
Total: $ ___________________________
Resource Sharing (if applicable)
Gov’t %____ $ _______________________

Performer % ____ $ _______________________

Place(s) of Performance

SUB-AWARDEE AND CONSULTANT

TEAM MEMBERS

(Add rows as necessary)

1. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-Profit ☐ Academia

2. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-Profit

3. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-Profit

4. Organization Name:

Technical POC Name:

Organization Type(s):
Choose all that apply:

☐ For-Profit ☐ Non-Profit

NOTE: Content recommendations are displayed in blue font and should be deleted by the proposer before submitting the Solution Summary.

Solution submissions are due by the date listed in the ISO Summary Information Section. All proposal documents must be submitted in .pdf, .odx, .doc, or .docx formats. All submissions must be written in English and all pages must be formatted for printing on 8-1/2 by 11-inch paper with 1-inch margins and sans serif font size not smaller than 11 point. Font sizes of 8 or 10 point may be used for figures, tables, and charts. Sections 1-4 below are limited to 8 pages total.

1. CONCEPT SUMMARY

Describe the Solution Summary concept with minimal jargon and explain how it addresses the ISO interest areas.

2. INNOVATION AND IMPACT

Clearly identify the outcome(s) sought and/or the problem(s) to be solved with the proposed technology concept. Describe how the proposed effort represents an innovative and potentially revolutionary solution to the ISO interest areas. Explain the concept’s potential to be disruptive compared to existing and emerging technologies. To the extent possible, provide quantitative metrics in a table that compares the proposed technology concept to current and emerging technologies, which may include:

· A progression of increasingly complex technical challenges.

· State of the art / emerging technology “baseline.”

· Aggressive metrics for each year of the proposed project.

· Summary of specific outcomes from the proposed project or concept.

3. PROPOSED WORK

Describe the final deliverable(s) for the project, key interim milestones, and the overall technical approach used to achieve project objectives. Provide a concrete research plan at a level of detail that can be used to assess novelty, scientific and technical merit, and feasibility. Discuss alternative approaches considered, if any, and why the proposed approach is most appropriate for the project objectives. Describe the background, theory, simulation, modeling, experimental data, or other sound engineering and scientific practices or principles that support the proposed approach. Provide specific examples of supporting data and/or appropriate citations to the scientific and technical literature. Identify adoption challenges to be overcome for the proposed technology to be successful. Describe why the proposed effort is a significant technical challenge and the key technical risks. ARPA-H expects projects to have substantial technical risk counterbalanced with the potential for transformative impact, which must be clearly addressed within the submission.

4. TEAM ORGANIZATION AND CAPABILITIES:

4.1 Indicate the roles and responsibilities of the organizations and key personnel comprising the Project Team.

4.2 Provide the name, position, and institution of each key team member and describe in 1-2 sentences the skills and experience they bring to the team. Key team members include the individuals who are expected to contribute to the scientific development or execution of the project in a substantive, measurable way.

5. BASIS OF ESTIMATE (BOE) - NOT INCLUDED IN THE PAGE LIMIT:

5.1 Identify a BOE that encompasses all costs and resources for the entire proposed project team. The BOE should include direct labor, materials, supplies, equipment, travel, profit/fee, indirect costs, and any other costs associated with the proposed project.

5.2 The BOE should identify whether resource sharing applies. Please further describe your value proposition and/or return on investment for this effort for the U.S. taxpayer beyond scientific or technical outcomes. The following table may be used:

Categories
Amount

Direct Labor (fully burdened)

Labor hours

Subcontracts/Consultants

Materials

Equipment

Travel

Other Direct Costs

Indirect Costs

Profit

Total (including all phases)

Resource Sharing (if applicable)

6. REFERENCES CITED – NOT INCLUDED IN THE PAGE LIMIT

For any references cited in the Solution Summary, provide uniquely identifying bibliographic information in this section, including first author, title, source (e.g., journal or book), year of publication, volume and page numbers (if applicable), and a persistent identifier, such as a DOI or PubMed ID, where available.

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