Project Grant R21CA303345
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a $593,557 Project Grant on March 18, 2026, under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to support research through February 28, 2031. This grant funds the development of novel magnetic resonance (MR) methods to enable real-time measurement and control of BPM31510, an emerging lipophilic tumor therapy composed of Coenzyme Q10 incorporated into a lipid...
- Federal Grant Award Summary Illuminant Surgical Inc. received a $1,107,943 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) awarded on September 12, 2025, with a completion date of August 31, 2027. This Phase II effort focuses on the continued development and validation of Skylight, a mixed-reality navigation platform designed to improve the accuracy and safety of image-guided biopsy procedures. The platform employs advanced...
- Federal Grant Award Summary The National Cancer Institute awarded The Leland Stanford Junior University a $368,294 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) for the period September 1, 2025 through August 31, 2028. This award supports the development of next-generation platforms for interrogating T cell receptor (TCR) specificity to identify and detect tumor antigens at the protein level. The project addresses a critical bottleneck in cancer...
- Federal Grant Award Summary The National Cancer Institute awarded The Leland Stanford Junior University a $584,521 Project Grant on August 8, 2025, under the Cancer Treatment Research program (CFDA 93.395) to investigate subclonal determinants of radiation response in soft tissue sarcomas. The research will deliver three primary products: (1) identification and validation of epigenetic changes, including DNA methylation and chromatin accessibility alterations, that confer radioresistance to...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded University of California, Los Angeles a $640,956 Project Grant on May 15, 2026, under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to develop an artificial intelligence-enhanced perfusion magnetic resonance imaging (MRI) tool for optimizing yttrium-90 (Y90) microsphere distribution in radioembolization treatment of liver cancer. The project, which extends through April 30, 2031, will deliver an...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a Project Grant of $119,172.00 under the Cancer Research Manpower program (CFDA 93.398) to support research addressing therapeutic response in non-small cell lung cancer (NSCLC). The project, initiated August 1, 2025, and completing July 31, 2027, focuses on developing computational approaches to integrate multi-modal and multi-omics biomedical datasets for improved...
- Federal Project Grant Award Summary Ramona Optics Inc. received a $306,872 Project Grant awarded on September 9, 2025, by the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) to develop a Multi-Camera Array Scanner (MCAS)—an advanced imaging system designed to rapidly digitize and automatically analyze three-dimensional fine-needle aspiration (FNA) cytology smears in real time. The MCAS technology addresses a critical gap in cancer diagnosis by enabling rapid...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $623,432 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) awarded on May 7, 2026, with a completion date of April 30, 2031. This award supports the development and refinement of the Cancer Vision Goggle (CVG), a head-mounted fluorescence-guided surgery (FGS) system designed to improve surgical outcomes in cancer procedures by...
- Federal Project Grant Award Summary The National Cancer Institute (NCI), under its Cancer Research Manpower program (CFDA 93.398), awarded a $100,228 Project Grant to The Leland Stanford Junior University to support biomedical research training and investigator-initiated cancer research. The award, obligated on December 1, 2026, with a completion date of June 30, 2029, funds research focused on the regulation of early breast cancer invasion by cancer-associated fibroblasts (CAFs). The research...
- Federal Project Grant Award Summary The National Cancer Institute awarded The Leland Stanford Junior University a Project Grant totaling $644,703 (awarded July 1, 2026, with completion anticipated June 30, 2031) under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to develop an advanced bone marrow organoid (BMO) culture system for acute myeloid leukemia (AML) research. The project delivers a human bone marrow organoid culture methodology that preserves the native bone...
The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a $395,973 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on June 9, 2026, with performance completion targeted for May 31, 2028. The award funds development and validation of an augmented reality (AR) surgical guidance system designed to improve breast cancer lumpectomy outcomes by projecting volumetric magnetic resonance imaging (MRI) data directly into the surgical field. This technology aims to reduce positive surgical margin rates—a primary driver of repeat surgeries—by nearly 50% through enhanced depth perception and intraoperative marker tracking integrated into commercial AR platforms. The deliverables include two primary research objectives: (1) optimization and comparison of aperture projection methods using phantom models of lumpectomy procedures, and (2) validation of the prototype AR-guided system through a pilot clinical study with 30 breast cancer patients. The project will generate paired comparative data between standard and AR-guided surgical techniques within the same patients, documenting the system's ability to reduce positive margin rates and minimize tissue overexcision. Upon completion, the system is expected to be positioned for future randomized controlled trials to establish clinical efficacy and support broader adoption in surgical oncology practice.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $396.0k | 6/11/26 |