Project Grant R01CA308814
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a $584,521 Project Grant on August 8, 2025, under the Cancer Treatment Research program (CFDA 93.395) to conduct a five-year research initiative (completion date: July 31, 2030) investigating subclonal determinants of radiation response in soft tissue sarcomas. The research will deliver three primary products: (1) identification and validation of epigenetic changes, including DNA...
- Federal Grant Award Summary The National Cancer Institute awarded Stanford University a Project Grant of $368,294 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) for the period of September 1, 2025 through August 31, 2028. This award supports the development of next-generation platforms for interrogating T cell receptor (TCR) specificity and identifying peptide-major histocompatibility complex (pMHC) tumor antigens. The research addresses a critical bottleneck in cancer...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a Project Grant of $119,172.00 under the Cancer Research Manpower program (CFDA 93.398) to support research addressing therapeutic response in non-small cell lung cancer (NSCLC). The project, initiated August 1, 2025, and completing July 31, 2027, focuses on developing computational approaches to integrate multi-modal and multi-omics biomedical datasets for improved...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a Project Grant of $133,598.00 under the Cancer Research Manpower program (CFDA 93.398) on June 23, 2025, with completion anticipated by May 31, 2027. This award supports research aimed at developing improved chemoprevention strategies for Familial Adenomatous Polyposis (FAP), a hereditary condition characterized by polyp formation and elevated cancer risk. The principal...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded $700,838 to the University of California, San Francisco under the Cancer Detection and Diagnosis Research program (CFDA 93.394) for a five-year Project Grant spanning April 1, 2026 through March 31, 2031. The award supports development and optimization of advanced magnetic resonance (MR) imaging and radiation therapy planning technologies to improve treatment outcomes for patients with primary and secondary liver tumors....
- Federal Grant Award Summary The National Cancer Institute awarded The Leland Stanford Junior University a $642,732 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. The award supports the development and deployment of novel single-cell genomic technologies to characterize molecular and phenotypic heterogeneity across all subtypes of endometrial carcinoma. The research will utilize Genotyping in Fixed Transcriptomes...
- Federal Project Grant Award Summary The Leland Stanford Junior University received a $135,774 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398) on July 10, 2025, with a completion date of June 30, 2027. This award supports research training and investigation into tumor suppressor genes (TSGs) and the overdominant model of tumor suppression in oncogenic KRAS-driven lung adenocarcinoma. The research employs advanced molecular and...
- Federal Grant Award Summary The Leland Stanford Junior University received a $1,033,055 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective September 8, 2025, through August 31, 2030. This award funds research focused on targeting cancer metastasis by inhibiting curvature-induced kinase activation. The project aims to develop therapeutic interventions for solid tumors by exploiting a newly...
- Federal Grant Award Summary The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research a $452,540 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on July 11, 2025, with a completion date of June 30, 2027. This award supports the development of a novel T-cell imaging paradigm utilizing positron emission tomography (PET) agents targeting CD8 and CD4 markers to provide real-time monitoring of endogenous T-cell trafficking, tumor...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $382,449 Project Grant to the University of California, Los Angeles under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on July 16, 2025, with completion targeted for June 30, 2027. This research project develops and validates advanced dual-nuclei magnetic resonance imaging (MRI) techniques to non-invasively differentiate between recurrent brain metastases (RBM) and radiation-induced necrosis (RN)...
Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a Project Grant totaling $593,557 on March 18, 2026, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to support research on novel magnetic resonance (MR) methods for monitoring and controlling BPM31510, an emerging lipophilic cancer therapeutic agent. The research initiative, spanning from March 2026 through February 2031, addresses a critical gap in cancer treatment translation by developing real-time measurement and response monitoring techniques for BPM31510, a coenzyme Q10 (CoQ10) lipid nanoemulsion formulation. The project builds on Stanford researchers' prior demonstration that BPM31510 exhibits differential cytotoxic effects on glioma cells while sparing normal tissue in vitro and achieves orthotopic glioma cure as a single agent in vivo when administered at the correct dose. This award directly supports the Cancer Detection and Diagnosis Research program's objective to develop diagnostic and prognostic technologies that improve cancer detection and enable personalized treatment monitoring. By creating appropriate MR-based real-time measurement methodologies for BPM31510 response, the research removes a significant translational barrier and facilitates clinical advancement of a potentially transformative cancer therapy. The project's focus on dose-dependent drug response monitoring through advanced imaging aligns with the program's emphasis on molecular and imaging biomarkers for treatment selection and disease monitoring across multiple cancer types.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $593.6k | 3/18/26 |