Project Grant R37CA296109
- This federal Project Grant award of $1,033,055.00 was provided by the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The funding supports research aimed at understanding and targeting the mechanisms of cancer metastasis. The project, titled "Targeting Cancer Metastasis by Inhibiting Curvature-Induced Kinase Activation," seeks to unravel the molecular pathways underlying how cancer cells acquire the...
- The Leland Stanford Junior University was awarded a $1,108,391.72 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) with a project period from January 1, 2025 to December 31, 2027. The grant supports research to define the most therapeutically relevant CAR T cell subsets in patients with large B cell lymphoma (LBCL) and overcome immune suppression mechanisms of resistance to CAR T cell therapy. Key research activities include following...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $119,172 to The Leland Stanford Junior University (Stanford University) from August 1, 2025 to July 31, 2027. The project aims to harness multi-modal and multi-omics data integration to decipher therapeutic response in non-small cell lung cancer. The research seeks to characterize the spatial interactions between tumor cells and their microenvironment using high-dimensional,...
- The Leland Stanford Junior University (Stanford University) was awarded a $642,732 Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393). The grant aims to develop and deploy novel single-cell technologies to unravel the genetic and phenotypic heterogeneity within endometrial carcinoma, a common but highly diverse form of uterine cancer. Specifically, the project will utilize the Genotyping in Fixed Transcriptomes (GIFT)...
- This federal Project Grant award of $640,522 from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) to The Leland Stanford Junior University supports research to elucidate how microbial microproteins modulate macrophage function, a critical coordinator of tumor immune response. The project aims to carry out high-throughput screens of thousands of microbial macromolecules to identify those that directly modulate macrophages, with the goal of enhancing cancer immunotherapy...
- This federal Project Grant award, valued at $469,381.00, was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The Leland Stanford Junior University. The award period runs from April 15, 2025 to April 14, 2027. The purpose of this grant is to fund research focused on "ENGINEERING CYTOTOXIC LYMPHOCYTES TO INFILTRATE OVARIAN CANCER TUMORS VIA METABOLITE-SENSING RECEPTORS". This advanced biomedical research aims to transform...
- This $680,507 Project Grant was awarded on April 1, 2025 by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to the University of California, San Francisco. The grant aims to elucidate mechanisms of cancer persister cell rewiring and identify druggable targets to eradicate persistence in KRAS-mutant non-small cell lung cancer. The key objectives are to: 1) illuminate signals that promote persistence in physiological contexts, 2) identify and validate targets that inhibit...
- The National Cancer Institute (NCI) awarded a $127,968 Project Grant under the Cancer Research Manpower (CFDA 93.398) federal grant program to The Leland Stanford Junior University (Stanford University) on December 24, 2024. The grant supports a research project titled "Investigating the Regulation of Cancer Cell Death by NFE2L1" with a planned completion date of August 31, 2026. The goal of this research is to better understand the molecular mechanisms of cancer cell resistance to...
- This Cooperative Agreement awarded by the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $1,281,520.00 in funding to The Leland Stanford Junior University to conduct research on the fundamental biological mechanisms of cancer metastasis, organ tropism, and immune evasion. The project aims to integrate genetic barcoding with single-cell profiling to uncover the key molecular drivers underlying metastatic fitness and diverse cancer cell states in pancreatic ductal...
- This federal Project Grant award of $187,887 from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower program) is supporting research at The Leland Stanford Junior University (Stanford University) to explore the role of extrachromosomal DNA (ecDNA) in HER2-amplified breast cancer. The key objectives are to investigate how HER2 ecDNA drives genome instability and treatment resistance in HER2-positive breast cancer, and to evaluate if combined targeting of HER2 and the S phase...
This federal Project Grant award of $584,521 was provided by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to The Leland Stanford Junior University (Stanford University) on August 8, 2025. The grant supports a research study to understand the non-genetic mechanisms that enable subclonal tumor populations to survive radiotherapy for soft tissue sarcomas. The key objectives are to: 1) identify and validate epigenetic changes that cause subclonal radioresistance, 2) define critical interactions between radioresistant subclones and non-malignant cells in the tumor microenvironment, and 3) develop approaches to non-invasively monitor radioresistant subclones. This research aims to improve the efficacy of radiotherapy for patients with soft tissue sarcomas and other cancers. The project period runs through July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $584.5k | 8/6/25 |