Project Grant R01EY038416
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded $173,016 to the Whitehead Institute for Biomedical Research under the Vision Research program (CFDA 93.867) for a project grant effective August 1, 2025, through July 31, 2027. This award supports systematic identification and mechanistic characterization of novel oxidative protective genes to prevent retinal pigment epithelium (RPE) degeneration in age-related macular degeneration (AMD). The research involves...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded New York University School of Medicine a $673,747 Vision Research project grant (CFDA 93.867) commencing June 1, 2025, and concluding May 31, 2030, to develop advanced optical imaging technology for early detection of age-related macular degeneration (AMD). The research focuses on advancing visible-to-near-infrared spanning optical coherence tomography (OCT) to achieve half-micron axial resolution for retinal imaging,...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a $638,625 Project Grant to the University of California, San Diego, effective August 1, 2025 through July 31, 2028, under the Vision Research program (CFDA 93.867). The award funds research to investigate the mechanisms of drusen formation in age-related macular degeneration (AMD), a leading cause of blindness affecting approximately 196 million people globally. The research employs a novel quartz crystal microbalance assay...
- Federal Grant Award Summary The National Eye Institute (NEI), administering funds under the Vision Research program (CFDA 93.867), awarded the University of Maryland, Baltimore a $249,000 Project Grant effective September 30, 2025, with completion targeted for August 31, 2028. This research project will develop and validate novel fluorescence lifetime imaging technologies to assess the retinal pigment epithelium (RPE) cell mosaic in the living human eye by characterizing intracellular pigment...
- Federal Project Grant Award Summary The National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) awarded $733,137 to the University of California, Los Angeles on September 15, 2025, to support research exploring how genetic variation influences disease progression and therapeutic response in age-related macular degeneration (AMD). The project, with completion targeted for March 31, 2030, will deliver scientific research products including refined classification of AMD...
- Federal Grant Award Summary Baylor College of Medicine received a $646,167 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective April 1, 2026 through March 31, 2031. The award funds investigations into the cellular and molecular mechanisms underlying Age-Related Macular Degeneration (AMD), the leading cause of vision loss in elderly populations. The research applies high-throughput functional genomics approaches to identify causal...
- Federal Project Grant Award Summary Tufts University School of Medicine received a $144,618 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective September 1, 2025 through March 31, 2028. The grant funds research investigating fucosylation as a mediator of limbal stem cell (LSC) viability. The research focuses on understanding how fucose, a monosaccharide component of the cell surface glycocalyx, influences the survival of limbal stem...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded The Schepens Eye Research Institute, Inc. a Project Grant of $545,948 under the Vision Research program (CFDA 93.867) to advance understanding of glaucoma pathophysiology. The award, effective April 1, 2026 through March 31, 2030, supports research investigating the role of reactive astrocytes in glaucoma progression and retinal ganglion cell (RGC) survival. The research aims to move beyond traditional neurocentric...
- Grant Award Summary The National Eye Institute's Vision Research program (CFDA 93.867) awarded a $3.56 million Project Grant to The Research Foundation for the State University of New York on August 1, 2025, with completion targeted for March 31, 2029. This research initiative investigates the relationship between nutritional metabolomics and age-related macular degeneration (AMD), a leading cause of vision loss in older adults. The project analyzes approximately 2,000 metabolites from...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded Cleveland Clinic Lerner College of Medicine of Case Western Reserve University a Project Grant totaling $615,928 (awarded April 15, 2026; completion March 31, 2030) under the Vision Research program (CFDA 93.867) to conduct mechanobiological research on Bruch's membrane during aging and its implications for age-related macular degeneration (AMD). The research will generate spatial and temporal matrisome...
Award Details: The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a $504,304 Project Grant to Tufts University School of Medicine on April 15, 2026, with a project completion date of March 31, 2031. The award supports research investigating the mechanistic basis of the gut-retina axis and its relationship to age-related macular degeneration (AMD) prevention. Research Products and Services: The project will deliver empirical findings on how gut microbiota composition influences retinal health through secondary bile acid production and other bacterial metabolites. Key research activities include conducting fecal microbiota transplantation experiments in mice, evaluating the protective effects of specific bacteria (Akkermansia muciniphila and Bacteroides thetaiotaomicron) on AMD-like retinal degeneration, and performing comprehensive metabolomic analysis of plasma, urine, and cecal samples to identify neuroprotective compounds. The research will generate mechanistic data on intestinal permeability, inflammation markers, and microbiome composition changes in response to dietary interventions, ultimately contributing to fundamental understanding of how dietary choices influence vision outcomes and potentially informing dietary recommendations for AMD prevention in older adults.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $504.3k | 4/17/26 |