Project Grant R01EY038063
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $255,722 to the University of California, Berkeley, effective September 15, 2025, through August 31, 2027. This Project Grant funds research investigating the role and regulation of a distinct optic nerve microglia population in glaucomatous neuropathy. The research addresses mechanisms of retinal ganglion cell degeneration during ocular hypertension (OHT) by examining...
- Federal Project Grant Award Summary Funding Agency: National Eye Institute (National Institutes of Health) Federal Program: Vision Research (CFDA 93.867) Award Amount: $624,743 Award Period: May 1, 2026 – April 30, 2030 Recipient: The Regents of the University of California, University of California, Berkeley UC Berkeley will conduct a four-year research project investigating the function and regulation of constitutive prostaglandin D2 (PGD2) and DP receptor signaling in retinal health and...
- Federal Grant Award Summary Award Overview The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a Project Grant of $175,293 to The Regents of the University of California, Berkeley, effective July 1, 2026, through February 28, 2031. This research initiative investigates the differential roles of transient receptor potential (TRP) cation channels—specifically TRPV1 and TRPA1—in modulating corneal mucin expression and bacterial defense mechanisms against...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $481,500 to the Regents of the University of California, doing business as University of California, Berkeley, effective September 1, 2025, through August 31, 2027. The project, titled "A Role for Retinal Waves in Vascular Development," will deliver research aimed at understanding neural-glial-vascular signaling mechanisms that influence blood vessel...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded a $902,000 Project Grant to The Regents of the University of California, San Francisco under the Vision Research program (CFDA 93.867) effective September 1, 2025, through August 31, 2027. This award funds research to characterize a novel GLIS1 knockout (KO) mouse model of glaucoma, addressing the critical need for therapeutic strategies targeting neuroprotection in primary open-angle glaucoma (POAG), a leading cause of...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a $255,340 Project Grant to The Regents of the University of California, San Francisco, effective May 1, 2026, through April 30, 2031, under the Vision Research program (CFDA 93.867). This award supports fundamental research into the development and regeneration of retinal ganglion cells in the vertebrate retina, with the goal of developing therapeutic strategies to restore vision in patients with glaucoma and other retinal...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $125,954 to the University of California, Berkeley for a two-year Project Grant (July 1, 2026 – June 30, 2028) to conduct fundamental research on the molecular mechanisms underlying synaptic specificity in the retinal direction-selective circuit. The research addresses how neurons form precise synaptic connections during development and investigates the relevance of these...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded $127,180 under the Vision Research program (CFDA 93.867) to The Regents of the University of California, San Francisco, effective July 1, 2026, through June 30, 2028. This two-year project grant funds basic science research investigating the role of perivascular retinal ganglion cells (RGCs) in regulating retinal vascular architecture and neurovascular resilience. The research focuses on a specialized subset of RGCs...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $143,031 to the University of California, Berkeley on December 4, 2025, with a completion date of May 31, 2028. This Project Grant funds computational modeling research investigating the role of spatial phase in the selectivity and invariance of neuronal responses in primary visual cortex (V1) and secondary visual cortex (V2) when processing intermediate-level features in...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $431,750 to the University of California Irvine under the Vision Research program (CFDA 93.867) effective May 1, 2026, through April 30, 2028. This exploratory project grant funds research into the novel mechanisms underlying obstructive meibomian gland dysfunction (O-MGD), a condition characterized by altered lipid synthesis, duct dilation, and inflammatory disease of the eye's oil-secreting glands. The research deliverables...
Federal Grant Award Summary The National Eye Institute (NEI) awarded a $633,742 Project Grant to The Regents of the University of California, Berkeley, effective July 1, 2026, through June 30, 2028, under the Vision Research program (CFDA 93.867). The award supports fundamental research investigating a novel lymphatic drainage pathway for aqueous humor in the eye—specifically, fluid drainage from Schlemm's canal to conjunctival lymphatic vessels rather than the conventional pathway to episcleral veins. This research addresses glaucoma, a leading cause of blindness affecting 80 million people worldwide, by characterizing the role of the conjunctival lymphatic pathway in aqueous humor drainage and intraocular pressure (IOP) regulation. The research deliverables include three primary objectives: (1) assessing the specific contribution of the conjunctival lymphatic pathway to aqueous humor drainage and IOP regulation; (2) investigating the effects of pro-lymphatic therapeutic treatment on the conjunctival lymphatic pathway; and (3) exploring therapeutic outcomes of pro-lymphatic treatment on ocular hypertension and glaucoma. The project builds on substantial preliminary data and aims to establish new mechanistic understanding and therapeutic strategies for glaucoma treatment, with potential applications to other lymphatic-related diseases. UC Berkeley will conduct the research at its Berkeley, California campus.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $633.7k | 6/24/26 |