Project Grant R21EY037926
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) is supporting research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to investigate the role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation. The $248,999 award, effective from May 1, 2025 to April 30, 2028, aims to elucidate how neuronal synaptic activity, specifically cholinergic and glutamatergic neurotransmitters,...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides funding to researchers at the University of California, San Francisco (UCSF) to study the neural mechanisms underlying visual processing and behavior after photoreceptor degeneration. The $237,588 award, spanning June 2025 through December 2027, will leverage the vertical optokinetic reflex (OKR) - a visual behavior that tracks global motion - to investigate how cone degeneration disrupts noise...
- This $437,250 Project Grant award from the National Eye Institute's Vision Research federal grant program (CFDA 93.867) aims to develop an integrated platform that combines 3D bioprinting, optogenetic stimulation, multi-electrode array (MEA) recording, and real-time fluorescence imaging to create a "visual-circuit-on-a-chip" for evaluating neural activity in stem cell-derived retinal disease models. The project, awarded to the University of California, San Diego, seeks to address...
- This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $127,861 to The Regents of the University of California, Berkeley to conduct research on the role and regulation of a distinct optic nerve microglia population in glaucomatous neuropathy. The research aims to elucidate how the lipoxin LXB4 regulates disease-associated microglia (DAM) in the optic nerve during ocular hypertension, a key mechanism in the neuroprotective effects of LXB4 against...
- This $517,600 federal Project Grant award was provided by the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), to The Washington University in Missouri. The funding supports a research project titled "Visual Feature Competition Between Central and Peripheral Retinal Pathways" over the period from July 1, 2025 to March 31, 2030. The key objectives of the project are to: 1) behaviorally assess whether larval zebrafish can perform eye fixation...
- This $192,900 federal Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) supports research at Albert Einstein College of Medicine to investigate how locomotion affects the flow of visual information between brain areas. The project will use high-density laminar probes to record population activity from multiple visual areas in mice under different locomotive contexts. The researchers will evaluate changes in inter-areal visual signal communication using...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) supports the development of a novel, noninvasive, and sensitive diagnostic method to measure retinal dysfunction. The $491,466 award will fund research at the University of California, San Francisco (UCSF) from January 1, 2025 to December 31, 2026. The project aims to create a scalable diagnostic tool that can detect the earliest signs of retinal diseases like diabetic retinopathy and retinitis pigmentosa,...
- This $429,016 federal Project Grant awarded by the National Eye Institute (CFDA 93.867 - Vision Research) to Oakland University supports research to identify the mechanisms by which a subset of retinal amacrine cells, called starburst amacrine cells, initiate and propagate spontaneous cholinergic waves in the developing retina. The objectives are to determine the distribution and properties of these cholinergic wave "pacemaker" cells (Aim 1) and to elucidate the calcium-dependent...
- This $464,903 federal Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) will support research at the University of Chicago to investigate how neuronal connections form in the retinogeniculate pathway during childhood development. The researchers will focus on understanding how neurons in the visual system make the correct connections, and how disruptions like closing one eye can impact this process. The goal is to gain insights into how...
- This federal Project Grant award of $123,794 from the National Eye Institute's Vision Research program (CFDA 93.867) supports research to reveal the fundamental mechanisms of visual selective attention. The principal investigator at the University of California, Los Angeles (UCLA) will leverage an invertebrate model system to identify the neural components and computations underlying object detection and saccadic control pathways. These studies aim to further the understanding of simple...
This $240,750 federal Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) aims to investigate the role of neural-glial-vascular signaling in the development of the eye's vasculature. The research has two main objectives: 1) Characterizing vasculature development and how it is altered in mice with modified retinal waves, using quantitative approaches and live imaging, and 2) Establishing the maturation of the glial-vascular unit through immunofluorescence and two-photon calcium imaging to monitor spontaneous calcium transients. The research will be conducted by the University of California, Berkeley and is intended to enable the lab to test new hypotheses about how neural activity influences normal and pathological vascular development, which is crucial for designing treatments for vascular defects like retinopathy of prematurity. The award period runs from September 1, 2025 to August 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $240.8k | 8/15/25 |