Project Grant R01EY036472
- This federal Project Grant award of $146,922 from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports research to investigate the role of ankyrins in mediating the development of synaptic connections between photoreceptors and their respective targets in the mammalian retina. The award to Baylor College of Medicine aims to elucidate the early molecular events that coordinate the selective wiring of photoreceptors, which is essential for...
- This federal Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) in the amount of $121,665 provides funding to the University of Wisconsin - Madison to conduct research on the effects of regional neural architecture on signal processing in the macaque retina. The project aims to investigate how cellular connection mechanisms, such as convergence and divergence, influence the sensitivity of the rod and foveal midget pathways across different regions of the...
- This $460,625 Project Grant was awarded by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) to Yale University. The grant will fund research to investigate the cellular and synaptic mechanisms underlying changes in retinal ganglion cell (RGC) activity following optic nerve injuries in mouse models of glaucoma. Specifically, the project aims to (1) determine the underlying mechanisms for altered RGC activity after increased intraocular pressure or...
- This federal Project Grant award of $428,349 from the National Eye Institute's Vision Research program (CFDA 93.867) supports research into the mechanistic assessment of retinal ganglion cell genesis. The award, with a performance period from July 1, 2025 to March 31, 2030, aims to investigate the shared gene regulatory network and downstream targets of the key transcription factors Atoh7, Pou4f2, and Isl1 that are required for proper retinal ganglion cell development. The research will be...
- This $540,971 Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) supports research at Northwestern University to classify and study the subcellular compartmentalization of displaced amacrine cells in the mouse retina. The key goals are to: 1) Establish a multimodal classification of displaced amacrine cell types by aligning morpho-electric properties with transcriptomic data, and 2) Measure the functional compartmentalization within amacrine cell neurites...
- The federal Project Grant award titled "NEURAL CIRCUITS UNDERLYING VISUAL REPRESENTATION IN THE MEDIAL ENTORHONAL CORTEX" was provided by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867). The award totaling $577,544 was granted to Yale University, with a project period from February 1, 2025 to January 31, 2030. The purpose of this award is to conduct a comprehensive research study to (1) determine the capacity for visual stimulus...
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $431,750 Project Grant to the University of Louisville to study the role of neurexin proteins in retinal structure and function. The grant, effective from September 1, 2025 to August 31, 2027, aims to 1) determine the function of three neurexin genes and their isoform-specific expression patterns within the retina, and 2) characterize the cell-type-specific expression of neurexin isoforms...
- The National Eye Institute (NEI) awarded a $437,310 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Rochester to conduct research on the molecular and physiological mechanisms of inner retinal remodeling in retinal degeneration. The research aims to elucidate the mechanisms behind genetic, morphological, and physiological changes in retinal ganglion cells that lead to decreased signal-to-noise ratio and corruption of retinal circuits, with the...
- This $429,016 federal Project Grant awarded by the National Eye Institute (CFDA 93.867 - Vision Research) to Oakland University supports research to identify the mechanisms by which a subset of retinal amacrine cells, called starburst amacrine cells, initiate and propagate spontaneous cholinergic waves in the developing retina. The objectives are to determine the distribution and properties of these cholinergic wave "pacemaker" cells (Aim 1) and to elucidate the calcium-dependent...
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) is supporting research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to investigate the role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation. The $248,999 award, effective from May 1, 2025 to April 30, 2028, aims to elucidate how neuronal synaptic activity, specifically cholinergic and glutamatergic neurotransmitters,...
This federal Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $1,599,303.00 in funding to Yale University from Sep 1, 2025 to Aug 31, 2028 to conduct research on the physiology and organization of retinal cell types. The key products and services to be delivered under this grant include: Understanding the physiological responses and anatomical properties of a new group of bipolar cells in the mouse retina that exhibit paradoxical "on" light responses, known as noncanonical bipolar cells (NBCs). Investigating the synaptic physiology of glutamate signaling in the retinal accessory on layer where these NBCs are located. Conducting connectomic and functional characterization of the synaptic circuits involving these NBCs and other retinal neurons. This research aims to provide new insights into the function and organization of these noncanonical retinal cell types and their interactions within the visual system.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.6m | 8/29/25 |