Project Grant 2426092
- This Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) provides $104,236.00 to support a team of undergraduate students from the University of Virginia in developing a low-cost, non-invasive, effective topical treatment for Staphylococcus-based cellulitis. The project aims to produce skin-penetrating antimicrobial peptides specific to Staphylococcus with the potential for scalable production. Through this effort, the students will receive hands-on...
- This Project Grant from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems provides $474,861 to North Carolina State University under the Engineering program (CFDA 47.041) from January 15, 2023 to December 31, 2027. The award will fund research to develop strategies for improving the ability of genetically engineered probiotic yeast to reside long-term in the gut, with the goal of enabling in situ biomanufacturing of therapeutic agents to...
- This $149,403 federal Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) to North Carolina Agricultural and Technical State University (NC A&T) aims to develop a "theragnostic" (therapeutic and diagnostic) system for inflammatory bowel diseases (IBD). The project integrates data science, synthetic biology, and additive manufacturing to: 1) model the complex interactions between host, microbial, and environmental factors underlying...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) grant award of $516,522 to the Rector & Visitors of the University of Virginia (UVA) will fund a three-year Research Experiences for Undergraduates (REU) site focused on combining experimentation with computational analyses to discover disease mechanisms and identify new treatments and cures. The REU site will recruit 10 undergraduate students each summer to engage in state-of-the-art systems bioengineering and...
- This Project Grant award of $600,000 from the National Science Foundation's Engineering program (CFDA 47.041) will support the University of Virginia's research to design innovative, biology-inspired adsorptive separation materials using peptides to purify new protein-based therapeutic medicines from contaminants. The project aims to advance the molecular understanding of protein adsorption behaviors and establish design rules for mixed-mode peptide ligands to enable more effective separation...
- This National Science Foundation (NSF) Project Grant, awarded under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), provides $168,690 to the Florida Institute of Technology Inc. (Florida TECH) to develop a theragnostic (therapeutic + diagnostic) system for inflammatory bowel diseases (IBD). The project aims to model the complex interplay of host, microbial, and environmental factors that trigger IBD using data science, and then leverage synthetic biology and...
- This $1,000,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports research by the University of California, San Francisco (UCSF) to design, build, and test synthetic signaling systems built from computationally-designed de novo protein components. The goal is to develop stable, tunable, and modular signaling systems capable of precisely controlling biological processes, with applications in biotechnology such as engineered cells for...
- This Project Grant award from the National Science Foundation's Division of Information and Intelligent Systems (CFDA 47.070 - Computer and Information Science and Engineering) aims to develop a cyber-physical system that uses microrobots to control and direct the differentiation of genetically engineered stem cells to form desired pancreatic tissue. The $499,181 project, which will run from September 1, 2023 to August 31, 2026, focuses on overcoming the challenge of recreating the complex 3D...
- This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University (SFSU) to develop a synthetic transhydrogenation module to enhance the production of valuable chemicals using engineered organisms. The key objectives are to: Elucidate the structural mechanisms underlying the autoregulation of the GltAB-GudB enzyme complex in Bacillus subtilis, which regulates glutamate metabolism and impacts...
- The National Science Foundation (NSF), through its Engineering program (CFDA 47.041), awarded a $300,000 project grant to the Texas A&M Engineering Experiment Station (Tees) for the "BRING-SYNBIO: ERYTHRITOL-DRIVEN AND SPATIOTEMPORAL-CONTROLLED PROBIOTICS FOR PRECISE DELIVERY OF CHECKPOINT-BLOCKING NANOBODIES" project. The goal of this project is to develop two genetic circuits in the E. coli Nissle 1917 probiotic strain that can sense signals in the tumor microenvironment and...
This Project Grant award of $104,917 from the National Science Foundation's (CFDA 47.074) Biological Sciences program will support a team of undergraduate students at the University of Virginia in developing a low-cost treatment for exocrine pancreatic insufficiency. The students will design and build a probiotic that secretes synthetic pancreatic enzymes, with the goal of providing this treatment solution for the International Genetically Engineered Machines (iGEM) competition in synthetic biology. The project will provide the student participants with hands-on training across STEM disciplines, including synthetic biology, molecular biology, and computational modeling, while also exposing them to global perspectives on innovation, strategic roadmapping, and professional networking opportunities. This award reflects the NSF's mission to advance scientific knowledge and support interdisciplinary research training for a diverse team of undergraduate students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $104.9k | 7/22/24 |