NOI - RCT NHP Sepsis Blood Samples

The National Institutes of Health Office of the Director is issuing a non-competitive combined synopsis/solicitation for high-resolution, untargeted metabolomics analysis using the Metabolon global metabolomics platform, with responses due June 15, 2026 at 9:00 AM EDT. The procurement is a brand-name purchase order intended for award to Metabolon without full and open competition under FAR 12.603 and is not expected to exceed the simplified acquisition threshold.

The work supports the National Heart, Lung, and Blood Institute Laboratory of Critical Illness in characterizing neutrophil metabolic profiles from a non-human primate bacterial sepsis model. Place of performance and delivery is NHLBI, 10 Center Drive, Building 10-CRC, Room 5E-3233, Bethesda, Maryland 20892. The platform must simultaneously detect and quantify over 5,000–6,000 biochemicals across diverse metabolic pathways. Contractor responsibilities include sample processing, metabolite extraction, LC-MS-based metabolomic profiling, metabolite identification and quantification, data normalization and quality control, and delivery of raw and processed datasets with supporting documentation. Period of performance is six months after receipt of order.

The NAICS code is 541380, Testing Laboratories and Services, with a small business size standard of $19.0 million; the requirement is not set aside for small business. The PSC is Q301, Reference Laboratory Testing. Responses must include unit price, list price, shipping and handling costs, delivery timeframe, F.O.B. point, product or catalog numbers, documentation demonstrating capability, Unique Entity Identifier, Taxpayer Identification Number, and business size certification. All offerors must be actively registered in the System for Award Management. Responses may be submitted electronically to nicholas.capobianco@nih.gov. The solicitation number is 75N98026Q00547.