This federal Project Grant award for $153,540 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research at Columbia University to perform human genome-wide association studies (GWAS) to identify genetic risk variants associated with urinary tract infections (UTIs). The research aims to discover novel genes and cell types involved in immune...
This $166,643 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports the development of robust phenotyping pipelines for early detection of collagen type IV-associated nephropathy (COL4A-AN) using electronic health records (EHR) data. The primary goal is to establish scalable phenotyping methods that leverage natural language processing (NLP) and...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to investigate the genetic basis of nephrotic syndrome and its impact on kidney function and disease. The $265,188 award aims to discover the association of genetic variations in the NPHS1 gene, which encodes the nephrin protein, with kidney traits and diseases in a large...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is funding research to develop a deep learning model that can diagnose urinary tract obstruction in children with antenatal hydronephrosis more accurately than current clinical standards. The $155,011 award, with a project period from March 15, 2025 to January 31, 2030, aims to create a multimodal...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to provide a mechanistic framework for understanding upper urinary tract (UUT) physiology, with the goal of developing diagnostics and treatments for conditions like vesicoureteral reflux (VUR) and hydronephrosis. The $1,154,840 award to Weill Medical College of Cornell University will fund research using a novel...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $176,244 to The Regents of the University of California, San Francisco (UCSF) to support a 5-year research and training plan. The goal is to prepare Dr. Gabriel Loeb to lead an independent academic research program focused on understanding the mechanisms underlying ciliary...
The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $243,750 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Trustees of the University of Pennsylvania. The grant will fund the development of novel methods to improve detection of mosaic chromosomal alterations (MCA) in non-neoplastic tissues like the kidney and blood. The project aims to create single-cell sequencing techniques and spatial...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $200,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Washington University in St. Louis. The goal of this R56 award is to delineate the molecular mechanism regulating autophagy in Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) caused by UMOD mutations. The university will use CRISPR/Cas9 technology to generate the first...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $200,000.00 to New York University School of Medicine to conduct a case-cohort study investigating novel determinants of risk for living kidney donors. The key objectives are to: 1) use qualitative research to inform recruitment strategies and messaging to maximize participation of...
This federal Project Grant award of $421,067.00, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research using kidney organoids to investigate the effects of in utero exposures, such as pregestational diabetes, on kidney development programs. The research aims to identify alterations to the normal differentiation of nephron progenitors and podocytes within the kidney...