Project Grant R56DE034473
- The Project Grant award of $205,000.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program, will support research to investigate the relationship between the oral microbiome and adverse outcomes in pediatric hematopoietic cell transplant recipients. The key products and services to be delivered under this award include: Collecting oral samples (supragingival plaque and saliva) and blood samples...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $198,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Pennsylvania State University (Penn State) to conduct research on integrating population-wide oral microbiome data to better understand health differences in the United States. The project, which will run from July 1, 2025 to June 30, 2027, aims to disentangle how an individual's background and socioeconomic factors...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $639,248 Project Grant to the University of Florida to assess the marginal associations between dental caries and periodontal diseases, and their determinants, in cross-sectional studies. The research will develop statistical methodologies to address the challenge of "informative cluster size" in analyzing correlated dental...
- The University of Massachusetts Lowell (UML) received a $540,629 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The funding supports a 2-year research project to study host-pathogen interactions and modulation in an in vitro model of early oral dysbiosis. The project leverages UML's expertise in developing 3D oral tissue models that mimic the native gingival environment to investigate the...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $155,500 Project Grant to The University of Iowa. The grant funds a study to identify the causal effects of preventive dental services, including comprehensive oral exams, prophylaxis, fluoride application, and dental sealants, on academic achievement among children enrolled in Medicaid in Iowa. The study aims to determine the ages at...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $219,132 Project Grant to Virginia Commonwealth University (VCU) under the Oral Diseases and Disorders Research program (CFDA 93.121). The funding will support a 2-year project titled "Demystifying DMFT/DMFS: Pragmatic Nationwide Assessment of Dental Caries Outcomes from NHANES." The project aims to develop advanced statistical methods for efficiently assessing dental caries experience using complex nationwide...
- This federal Project Grant award of $163,411 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), supports research to characterize the nutritional niches and interactions between Streptococcus mutans, a primary driver of dental caries, and other commensal oral streptococci species. The research aims to understand how these microcolony biofilm structures form, the interactions between S....
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $620,000 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the Regents of the University of Minnesota. The grant supports research to identify natural products synthesized by the bacteria Streptococcus mutans that can inhibit the growth of Enterococcus faecalis, a leading cause of infected root canals. The research aims to characterize these anti-bacterial and anti-biofilm natural...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $219,660 Project Grant to the Regents of the University of Michigan to conduct research on "Intercepting the Evolution of Pro-Tumoral Myeloid Cells During the Initiation of Oral Cancer". This project aims to investigate how myeloid cells in precancerous lesions develop suppressive phenotypes that inhibit anti-tumor immune...
- This Project Grant award of $470,279 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to study the impact of bacterial oxidative stress responses on the ecology and pathogenicity of oral streptococci. The research project, conducted at the University of Alabama at Birmingham (UAB), will identify and characterize the hypochlorous acid (HOSCN) response mechanisms in oral streptococci, particularly...
The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded a $511,706 Project Grant to the University of Florida for a 3-year study to determine whether frequent standardized oral care using human milk reduces oral/intestinal inflammation and microbial dysbiosis, leading to improved neonatal outcomes and reduced cost of care in preterm very low birth weight infants. The study aims to evaluate the effect of frequent standardized oral care using human milk on oral inflammation (Aim 1) and characterize the metagenomic composition of the oral and intestinal microbiome (Aim 2) in preterm VLBW infants. The proposed research involves a secondary analysis of data from an ongoing randomized controlled trial of 168 racially diverse preterm VLBW infants randomized into 3 groups receiving different oral care regimens over 4 weeks after birth. The analysis will also assess the cost and cost-effectiveness of the intervention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/17/25 | ||
| Not listed | $511.7k | 8/19/25 |