The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $219,132 Project Grant under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121) to Virginia Commonwealth University (VCU). The project aims to develop a pragmatic, interpretable index model for assessing national-level dental caries experience using data from the National Health and Nutrition Examination Survey (NHANES). Specifically, the project will: (1) construct and validate a...
The National Institute of Dental and Craniofacial Research (NIDCR) has awarded a $161,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Case Western Reserve University to develop new statistical methods for analyzing the causal effects of individual components within bundled interventions. The research aims to elucidate the assumptions required for causal mediation analysis, propose a novel "cluster-specific interventional effect" estimand,...
The federal Project Grant award R35DE034352 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), aims to advance oral health equity through integrating patient, provider, and population-based approaches. The $999,776.00 grant, awarded on Sep 13, 2024, will fund research to strengthen the scientific basis for innovations in population approaches to improving dental care access, utilization, and...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $185,918 to Brigham & Women's Hospital Inc. to evaluate the impact of Medicaid coverage for treatment of periodontal disease on oral and comprehensive health outcomes. The project aims to assess the effect of this coverage on tooth loss, emergency department use for dental problems, oral healthcare costs, and...
The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), awarded a $163,411 Project Grant to The Ohio State University to conduct research on the interactions between health-associated and disease-causing oral bacteria within dental biofilms. The research project, titled "Nutritional Niches Within Supragingival Biofilms," aims to understand how the bacteria Streptococcus mutans, a primary...
This $241,500 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, will fund research to identify diffusible small molecules that regulate the replication of the oral bacterium Porphyromonas gingivalis. The key objectives are to establish the identity of growth-promoting cues produced by different strains of P. gingivalis and the early colonizer Veillonella parvula that support P....
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $381,216 to conduct research on the role of the ectonucleotidase CD73 in periodontal health and disease. The research aims to delineate how CD73 deficiency leads to metabolic dysfunction and inflammation in gingival fibroblasts, and study how this impacts the stromal-osteoclast axis and influences periodontal...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $499,440 to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to develop and evaluate novel, biostable and multifunctional dental resin composites and adhesives. The goal is to create superior dental restoration materials that resist hydrolysis, enzymolysis, and bacterial attack, and possess antimicrobial,...
This $248,999 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research to investigate the role of CD4+ memory T cell subtypes in the recurrence of periodontal disease. The project aims to: 1) identify the spatiotemporal development of CD4+ memory T cells in periodontal tissues, 2) elucidate the pathogenicity of CD4+ memory T cell subtypes induced by periodontal disease,...
The federal Project Grant award R03DE034043, funded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research to identify the causal relationship between oral health and heart disease. The $331,999 award to Lehigh University will build upon previous research showing an association between oral health and systemic health, including periodontitis and heart disease. The project will use a...