Project Grant R03DE034751
Award Date
6/1/25
Completion Date
5/31/27
Dollars Obligated
$310K
Federal Agency
National Institute of Dental and Craniofacial Research
Federal Grant Program
93.121
Assistance Type
Project Grant
Place of Performance
Minnesota, USA
Similar Awards
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $5,700,915 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the Regents of the University of Michigan. This 5-year grant, effective September 12, 2024, aims to develop a new class of anti-caries therapies that target the species-specific susceptibilities of oral pathogens like Streptococcus mutans and Candida albicans to fluoride. The project will leverage a multiscale approach to...
The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), awarded a $163,411 Project Grant to The Ohio State University to conduct research on the interactions between health-associated and disease-causing oral bacteria within dental biofilms. The research project, titled "Nutritional Niches Within Supragingival Biofilms," aims to understand how the bacteria Streptococcus mutans, a primary...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant (CFDA 93.121 - Oral Diseases and Disorders Research) to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania, for $460,885.00. The grant, with a period of performance from March 10, 2025 to February 28, 2030, supports research to investigate how the fungus Candida albicans interacts with the bacterium Streptococcus mutans to modulate the...
The federal Project Grant award R15DE034550, totaling $838,322.00, was granted by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The award supports the construction of an arrayed transposon mutant library for the dental caries pathogen Streptococcus mutans and the use of this library to study genetic determinants of sucrose-mediated biofilm formation, a critical virulence trait. The project aims to...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $656,315 to Temple University to conduct research on the pathogenesis of oral microbes triggered by the cyclic deformation of biomaterials. The overarching goal is to mechanistically study the effect of biomaterial cyclic strain on the pathogenesis of the fungal strain Candida albicans and denture-associated...
This $505,530 Project Grant was awarded on September 16, 2024 by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The grant supports research led by the University of Florida to investigate the role of functional amyloid formation in the bacterium Streptococcus mutans, which is a primary cause of dental caries. The project aims to explore the relationships between S. mutans amyloid-forming proteins, DNA...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121) provides $232,500.00 to the University of Kansas Medical Center Research Institute, Inc. (KUMCRI) to explore the role of arginine phosphorylation in the physiology of Streptococcus bacteria. The research aims to understand the function of this novel post-translational modification in Streptococcus mutans, a dental...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $249,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Iowa State University of Science and Technology. The grant, running from August 16, 2024 to August 15, 2027, aims to elucidate the mechanism of action and impact of radical-S-adenosylmethionine ribosomally synthesized and post-translationally modified peptides (RAS-RIPPs) produced by oral Streptococcus bacteria on the human...
This Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), will support research to investigate the role of T cell response in Aggregatibacter actinomycetemcomitans (AA)-associated periodontal disease. The $248,627 award, with a project period from January 1, 2025 to December 31, 2029, will be performed by the Regents of the University of Minnesota. The research aims to...
This Project Grant award of $155,500 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) will support a comprehensive examination of the oral virome and its interactions with the microbiome. The research aims to shed light on the role of viruses in maintaining oral health and contributing to disease, with the potential to inform the development of alternative treatments such as phage therapies. By mining...