Project Grant R50EB038043
- The National Institute of Child Health and Human Development awarded Boston Children's Hospital $356,000 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to develop artificial intelligence models that predict neurocognitive outcomes in children with congenital heart disease by integrating clinical, surgical, genomic, and neuroimaging data. The research addresses the gap that nearly half of children and adolescents with...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Children's Hospital Corporation (Boston Children's Hospital) $267,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and expand the Fetal and Neonatal Development Imaging (FEDI) open-source software platform for analyzing early brain development via magnetic resonance imaging. The project addresses a critical gap in...
- The National Institute of Child Health and Human Development awarded The Children's Hospital Corporation $775,598 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to develop machine-learning algorithms that automatically detect classic metaphyseal lesions—fractures highly specific to inflicted infant trauma—in skeletal survey radiographs. The recipient, doing business as Boston Children's Hospital, will train algorithms on both...
- The National Heart, Lung, and Blood Institute awarded The Children's Hospital Corporation, doing business as Boston Children's Hospital, $857,878 for a Project Grant (R01HL188153) on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds development and evaluation of pediatric cardiac foundation models—machine learning models pre-trained on large volumes of unlabeled electrocardiogram (ECG), echocardiogram (ECHO), chest X-ray, and clinical text...
- The National Institute of Child Health and Human Development awarded Massachusetts General Hospital $681,793 on June 23, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to map the neuroarchitecture and connectivity development of the human cerebellum during the first postnatal year using cross-scale imaging techniques. The research addresses the gap between in vivo and ex vivo imaging of perinatal cerebellar injury, which occurs in up to 19% of...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $580,605 to The Children's Hospital Corporation, doing business as Boston Children's Hospital, on August 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating the organization, plasticity, and regenerative capacity of reticulospinal neurons...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded Massachusetts Institute of Technology $436,242 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support predoctoral training in neuroscience and cognitive science. MIT's Department of Brain and Cognitive Sciences will deliver interdisciplinary graduate training spanning cellular and...
- Federal Project Grant Award Summary Boston Children's Hospital received a $1.27 million Project Grant (R01) from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective August 1, 2025 through July 31, 2027. The award supports collaborative research investigating the mechanisms through which transposable element (TE) mobilization and disrupted messenger RNA (mRNA) translation impair neural progenitor cell (NPC)...
- Federal Grant Award Summary Boston Children's Hospital received a $267,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 1, 2025, with completion anticipated by July 31, 2027. The award funds research to identify shared molecular mechanisms underlying congenital heart disease (CHD) and neurodevelopmental delay and disability (NDD) by characterizing dysregulated gene expression in...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services, awarded The Johns Hopkins University $133,432 on April 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the neurometabolic trajectory of the developing brain. The recipient will use magnetic resonance spectroscopy and imaging techniques to map multiple neurometabolites simultaneously in infants and young children,...
The Department of Health and Human Services National Institutes of Health Office of the Director awarded The Children's Hospital Corporation, doing business as Boston Children's Hospital, $177,927 under the Trans-NIH Research Support program (CFDA 93.310) on September 1, 2026, to develop and maintain a software package of deep neural networks for robust brain age estimation and to provide ongoing technical support for five NIH-funded research projects. The award funds development of artificial intelligence software tools to quantify brain development on brain magnetic resonance imaging and to enable transfer learning that trains AI models on large-scale datasets for application to smaller datasets. The deliverables include an AI software tool to study brain aging mechanisms as a biomarker across the lifespan and technical support for the Healthy Brain and Child Development National Consortium (U01DA055353), a longitudinal study of 7,500 mothers and children enriched for prenatal substance use; a project exploring multimodal brain MRI phenotypes and cognitive outcomes in adults with congenital heart disease (R01HL152358); the Consortium of MRI Biomarkers in Neonatal Encephalopathy (COMBINE) (R61/R33 NS126792) to predict outcomes in hypoxic ischemic encephalopathy; brain MRI analysis to predict seizure onset for Sturge-Weber Syndrome (R21TR004265); and a fifth NIH-funded project. Performance occurs at Boston Children's Hospital in Boston, Massachusetts, through May 31, 2029. The award is classified as a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $177.9k | 8/20/26 |