Project Grant R01NS146411
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $642,712 to The University of Texas Southwestern Medical Center on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate adult neurogenesis as a strategy for improving urinary function after contusion spinal cord injury. The project systematically examines...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Boston Children's Hospital $674,950 on January 16, 2026, to dissect neural circuits that mediate top-down control of sympathetic nervous system functions under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). Boston Children's Hospital will conduct basic neuroscience research analyzing...
- The National Institute of Neurological Disorders and Stroke, a division of the Department of Health and Human Services National Institutes of Health, awarded The Ohio State University $586,866 on May 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate a cellular transplantation therapy for cervical spinal cord injury using human induced pluripotent stem cell-derived deep cortical neurons. The recipient will...
- The National Institute of Neurological Disorders and Stroke awarded the Trustees of Boston University $173,128 on January 25, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop trehalose-based coacervates for biomolecular and cellular delivery to improve wound healing in spinal cord injury. The research addresses the challenge of delivering therapeutic molecules and grafted cells to spinal cord lesion sites while...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $226,500 on August 21, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to characterize spinal pain and non-pain pathway activity and responses in people with chronic spinal cord injury and neuropathic pain. The research will compare...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Boston Children's Hospital $577,573 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds functional validation of candidate genes implicated in refractory focal epilepsy, with emphasis on mosaic variants in mTOR pathway genes and non-mTOR genes such as SLC35A2. Boston Children's...
- The National Institute of Neurological Disorders and Stroke awarded New York University $638,783 on May 24, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how mammalian posterior group Hox transcription factors diversify their function to pattern the spinal cord during embryonic development. Research activities span two primary aims: examination of protein domains and specific Hox amino acids in HOXC9 and HOXC13...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Boston Children's Hospital a $489,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for the period July 1, 2025 through June 30, 2027. This R21 exploratory research grant supports a collaborative investigation into stimulus-responsive microproteins in human microglia-like cells, focusing on mRNA translational...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $660,613 to The Trustees of Columbia University in the City of New York on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on spinal cord stimulation as a combination therapy to enhance motor function in spinal muscular atrophy (SMA). The research...
- The National Institute of Neurological Disorders and Stroke (NINDS), a component of the Department of Health and Human Services National Institutes of Health, awarded $646,936 to the Regents of the University of California, San Francisco on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Project Grant R01NS142318). The award funds research investigating the inflammatory mechanisms underlying motor and sensory...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $580,605 to The Children's Hospital Corporation, doing business as Boston Children's Hospital, on August 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating the organization, plasticity, and regenerative capacity of reticulospinal neurons following spinal cord injury. The project will characterize the functional organization of distinct reticulospinal neuron populations and their roles in controlling spinal functions under intact conditions; assess whether different reticulospinal neuron populations causally contribute to spontaneous functional recovery after incomplete spinal cord injury using advanced technologies; and employ a newly developed method to selectively deliver neurotrophic factors targeting reticulospinal neurons and/or corticospinal neurons to spinal lesions, evaluating their effects on axon regeneration and functional recovery after severe spinal cord injury. Collectively, the research aims to provide insights into the organization, plasticity, and regenerative potential of reticulospinal neurons and to pave the way for novel therapeutic strategies to treat spinal cord injury. The period of performance runs from August 7, 2026, through May 31, 2031. Work is performed in Boston, Massachusetts.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $580.6k | 8/6/26 |