Project Grant R21EB040284
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded The Children's Hospital Corporation, doing business as Boston Children's Hospital, $177,927 under the Trans-NIH Research Support program (CFDA 93.310) on September 1, 2026, to develop and maintain a software package of deep neural networks for robust brain age estimation and to provide ongoing technical support for five NIH-funded research projects. The award funds development of artificial...
- This $1,336,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program supports the development of a rapid, motion-robust, and low-gadolinium MRI technology for pediatric brain tumors. The key objectives are to (1) develop cutting-edge technologies for rapid, motion-robust, and quantitative MRI scans to reduce sedation needs...
- The National Institute of Child Health and Human Development awarded Boston Children's Hospital $356,000 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to develop artificial intelligence models that predict neurocognitive outcomes in children with congenital heart disease by integrating clinical, surgical, genomic, and neuroimaging data. The research addresses the gap that nearly half of children and adolescents with...
- The National Institute of Child Health and Human Development awarded The Children's Hospital Corporation $775,598 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to develop machine-learning algorithms that automatically detect classic metaphyseal lesions—fractures highly specific to inflicted infant trauma—in skeletal survey radiographs. The recipient, doing business as Boston Children's Hospital, will train algorithms on both...
- The National Institute of Biomedical Imaging and Bioengineering awarded Northeastern University $219,818 on April 27, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a fully integrated electro-optic sensor for real-time MRI-guided interventions. The award funds development of an interventional device sensor that addresses safety and imaging limitations in MRI-guided procedures. Current active devices for...
- The National Institute of Child Health and Human Development awarded Massachusetts General Hospital $681,793 on June 23, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to map the neuroarchitecture and connectivity development of the human cerebellum during the first postnatal year using cross-scale imaging techniques. The research addresses the gap between in vivo and ex vivo imaging of perinatal cerebellar injury, which occurs in up to 19% of...
- The National Institute of Child Health and Human Development awarded the University of Illinois $498,000 on February 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to investigate neural markers of developmental delays in premature and full-term infants. The recipient will chart brain development using electroencephalography (EEG) during well-baby visits at 4, 9, and 12 months at a primary care clinic and at a 24-month follow-up lab visit,...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services, awarded The Johns Hopkins University $133,432 on April 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the neurometabolic trajectory of the developing brain. The recipient will use magnetic resonance spectroscopy and imaging techniques to map multiple neurometabolites simultaneously in infants and young children,...
- The National Institute of Biomedical Imaging and Bioengineering awarded Sloan-Kettering Institute for Cancer Research $636,110 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop motion-tolerant pediatric MRI technology that reduces anesthesia dependence in tumor imaging. The funded research develops deep learning reconstruction techniques combined with radial k-space acquisition to compensate for...
- The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $249,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop engineering strategies that reduce the electromagnetic shielding burden of conventional superconducting MRI systems. The recipient will design, optimize, and experimentally validate passive and active...
The National Institute of Biomedical Imaging and Bioengineering awarded The Children's Hospital Corporation (Boston Children's Hospital) $267,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and expand the Fetal and Neonatal Development Imaging (FEDI) open-source software platform for analyzing early brain development via magnetic resonance imaging. The project addresses a critical gap in neuroimaging tools designed for fetal and neonatal populations. Current MRI analysis software is configured for older children and adults and does not account for the distinct challenges of fetal and neonatal imaging, including low signal-to-noise ratio, unpredictable motion, and unique anatomical characteristics. FEDI will enable researchers and clinicians to study white matter tracts, brain connectivity, and microstructural changes in early development with greater precision. Work is structured around three aims: developing a comprehensive fetal brain tractography workflow using advanced diffusion MRI techniques; integrating brain structure segmentation and white matter tract delineation methods in collaboration with radiologists and neurologists; and ensuring user accessibility through Conda and Docker installation support and extensive documentation. The award funds work performed in Boston, Massachusetts, with a period of performance from September 1, 2026, through August 31, 2028. This is a project grant, an assistance type supporting hypothesis-driven research into biomedical imaging technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $267.0k | 8/18/26 |