Project Grant R43HD089761

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

FEND-TB Project Grant Summary Rutgers, The State University of New Jersey (RBHS-School of Nursing) received a $3.09 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 10, 2025, with a completion date of August 31, 2030. The grant supports the development and evaluation of tuberculosis (TB) diagnostic tools and drug susceptibility tests (DSTs) through a...

FAST-TB Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $3.5 million through the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, San Francisco on June 8, 2026, to support the Facilitating Accelerated Science and Translation for TB Regimen Development (FAST-TB) initiative through May 31, 2031. This project grant delivers shared infrastructure and durable resources designed to accelerate the evaluation,...

Federal Project Grant Award Summary Pace Diagnostics, Inc. received a $600,000 Project Grant from the Centers for Disease Control and Prevention (CDC) under the CDC Investigations and Technical Assistance program (CFDA 93.283), awarded on September 30, 2025, with a completion date of March 31, 2026. The award supports the development of an ultrasensitive urine-based tuberculosis (TB) antigen rapid detection test for diagnosing active tuberculosis. This diagnostic tool represents the program's...

This $991,832 Cooperative Agreement awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a novel rapid antibiotic susceptibility testing (AST) platform by Astek Diagnostics Inc., a minority-owned small business in Halethorpe, Maryland. The project aims to adapt the company's previously developed urine cartridge technology for use with cerebrospinal fluid and wound effluent specimens, characterize...

The National Science Foundation awarded PZA Innovation LLC a $270,509 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop reliable pyrazinamide susceptibility testing at neutral pH. The grant period runs from January 1, 2022 through October 31, 2023. Under this award, PZA Innovation LLC will deliver products and services focused on advancing science and engineering research and innovation leading to breakthrough technologies for national and...

The National Science Foundation (NSF) awarded a $305,000 SBIR Phase I Project Grant to Giant Biosystems Inc. on March 1, 2025. The project aims to develop a rapid, point-of-care antimicrobial susceptibility testing (AST) kit that can provide results on the same day a sample is taken. This is expected to help physicians utilize the most effective antibiotics sooner, reducing antimicrobial resistance and associated economic burdens. The proposed microfluidic platform is designed to generate...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics. The protocell technology uses...

Federal Cooperative Agreement Summary Prompt Diagnostics, Inc. received a $1.25M Cooperative Agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), awarded June 15, 2025, with completion targeted for May 31, 2027. The company is developing an automated, multiplexed point-of-care diagnostic platform for rapid detection and quantification of Treponema pallidum infections (syphilis). The solution integrates magnetic...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...