Project Grant 2319391

Award Date 8/15/23
Completion Date 7/31/27
Dollars Obligated $2.2M
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Atlanta, GA 30333, USA
Similar Awards
Cornell University received a $100,000 Project Grant award from the National Science Foundation's Technology, Innovation, and Partnerships program to develop a cell-free biosensing platform integrating transmembrane proteins. The award period is from July 1, 2022 to December 31, 2022. Specifically, the university will utilize recent advances in biotechnology and bioelectronics to establish a process for rapidly assembling customized transmembrane proteins into a biomimetic sensing device without...
This $1,200,000 federal Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) aims to develop innovative sensing technologies that will enable more frequent and comprehensive blood and urine testing to improve early disease detection. The University of California, Berkeley is the prime awardee and plans to integrate biosensors enabled by DNA nanotechnology with complementary metal-oxide-semiconductor...
This $399,935 Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing. The key technical activities include: 1) advancing 3D manufacturing techniques for electrodes to enhance fabrication precision and performance; 2) miniaturizing actuation,...
The National Science Foundation (NSF) awarded a $300,000 Project Grant under its Biological Sciences program (CFDA 47.074) to the Georgia TECH Research Corporation for the "TOOLS4CELLS: EAGER: A MOLECULAR PURSUIT FOR THE ENGRAM: MICROFLUIDIC TEMPORAL TRANSCRIPTOMICS FOR SINGLE CELL LEARNING" project. This 2-year effort aims to develop innovative microfluidic tools and workflows to investigate the role of non-coding RNA in learning and memory storage in single-celled organisms. Key...
The Georgia Tech Research Corporation was awarded a $1,077,799 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences on September 1, 2021 to complete work by August 31, 2025. The grant falls under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and enhancing understanding of major problems. Specifically, the grant will...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $257,807 Project Grant (CFDA 93.286) to the University of California, San Diego (UCSD) to develop a living biosensor technology for rapid, low-cost DNA diagnostics. The proposed project aims to create a hybrid living biosensor/lateral flow assay that can detect and analyze DNA sequences in raw samples without extensive purification. The biosensors will leverage bacterial competence and CRISPR-Cas systems to...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $426,036 Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia TECH Research Corp, also known as the Office of Sponsored Programs, a non-profit research organization and state institution of higher education associated with the Georgia Institute of Technology. The grant aims to identify and characterize oligonucleotide-based ligands as alternatives to antibodies for protein...
The National Science Foundation (NSF) awarded a $2,814,550 Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia Tech Research Corporation to develop next-generation biological security systems. This 5-year research effort aims to transition biological security from an operational technology platform to a biologically intrinsic informational technology platform. The project will involve the convergence of biological engineering, cybersecurity principles, and chemical...
This $242,687 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to develop a next-generation nanopore biosensor technology for the ultrasensitive detection and quantification of multiple infectious disease biomarkers at the point-of-care. The key objectives are to: (1) optimize a highly sensitive, robust, and reproducible nanopore biosensor; (2) enable specific biomarker detection through automated immunoprecipitation and novel signal...
This $153,680 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research by Georgia Tech Research Corporation to develop predictive spatial omics models using graph-based and generative learning approaches. The goal is to map and interpret hidden tissue features to better understand the molecular and structural differences across subcellular and tissue architectures in normal and aberrant biological phenotypes. The 5-year project...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics.

The protocell technology uses cell-free gene expression in aqueous droplets to sense target molecules and communicate with a central "receiver" protocell that integrates the signals to provide a diagnostic readout. This modular approach allows the platform to be easily adapted for different medical conditions. The project also includes efforts to enhance the efficiency and robustness of the protocell system for field use, with a focus on addressing zinc deficiency, a major global health challenge. In addition to the medical diagnostic applications, the project explores environmental applications of the proposed platform. The work is expected to have broad societal impact by improving access to diagnostics, particularly in underserved areas.

Generated 5/14/24, 5:38 AM