This $305,000 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) was granted to Giant Biosystems Inc., a small disadvantaged business, to develop a rapid point-of-care antimicrobial susceptibility testing (AST) kit. The key products to be delivered include: A novel microfluidic platform for rapid (6-9 hours) and precise AST, providing actionable results faster than current methods (3-5 days). This will enable...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) Project Grant award of $305,000 to Resonantia Diagnostics, Inc. aims to develop a rapid point-of-care diagnostic platform capable of identifying pathogens and determining their antimicrobial susceptibility within 60 minutes. The project will focus on advancing an acoustic sensing technology to: (1) demonstrate accurate antimicrobial susceptibility testing at low pathogen loads, (2)...
The federal Project Grant award R01AI179891, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the design and development of a rapid phenotypic drug susceptibility testing system for tuberculosis (TB). The $1,350,312 award aims to develop a novel fluorescent trehalose-based diagnostic test, termed TRE-DST, that can quickly and accurately detect drug resistance in Mycobacterium...
This Small Business Innovation Research (SBIR) Phase II Cooperative Agreement, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a novel rapid antibiotic susceptibility testing (AST) platform. The $991,832 award will enable Astek Diagnostics Inc., a minority-owned for-profit company, to adapt their previously developed urine cartridge for use with cerebrospinal fluid and wound effluent specimen...
This Project Grant award of $299,170 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to demonstrate the feasibility of a rapid, equitable antibiotic susceptibility test (AST) for urinary tract infections (UTIs). The goal is to develop the Metabolic Amino Acid Phenotyping (MAAP) test kit, which uses a lateral flow assay to provide susceptibility profiles for UTI-causing bacteria, including E....
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) aims to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The $274,362 award to RT Microdx Inc., a minority-owned and small disadvantaged business, will focus on optimizing a DNA-based test that leverages isothermal amplification and pH-sensitive polymers to provide accurate and user-friendly results...
This Project Grant award of $275,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The award recipient, Informuta, Inc., will establish the feasibility of leveraging mutational signatures found in bacterial DNA to predict antibiotic resistance status. The project aims to...
The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Macula Vision Systems Inc., a for-profit organization, supports the development of a novel microscopy platform to automate the interpretation of microbiology lab tests performed in hospitals. The project aims to address the shortage of trained lab technicians by engineering a specialized light source, customized camera, and AI-enabled algorithms to analyze...
This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to Bactria Pharmaceuticals LLC is providing $274,937 to develop therapeutic drugs that restore antibiotic sensitivity in bacteria that cause severe healthcare-associated infections. The goal is to combat antimicrobial resistance in gram-negative pathogens through the use of small molecule efflux pump inhibitors (EPIs). The project involves three key activities: cryo-electron microscopy to understand...