Project Grant R43DK129132
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Delphi Stem, Inc. $306,863 on August 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop a framework for evaluating type 2 diabetes medication efficacy using patient-derived cellular models. The recipient will generate personalized islet-like aggregates from patient cells to predict drug responsiveness and tailor treatment regimens, with the goal of improving...
- Federal Project Grant Award Summary Award Details: The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $464,750 Project Grant to Harvard Medical School (President and Fellows of Harvard College) on September 11, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research through August 31, 2027, and will be conducted in Massachusetts. Products and Services: This Project Grant funds the...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Pittsburgh $812,862 on June 12, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify novel biomarkers of early progressive kidney function decline in type 1 diabetes. The research will use urinary and plasma peptidomics—analysis of synthesized peptides and protein degradation fragments—to discover prognostic markers that predict diabetic...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Daecos LLC $619,274 on August 6, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and validate an artificial intelligence-driven clinical decision support system for predicting acute dialysis needs in critically ill patients. Daecos will refine its proprietary algorithms using retrospective data from three UC San Diego hospitals, deploy the system within UC...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $825,255 to The University of Texas Health Science Center at San Antonio on April 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify and validate metabolite markers of diabetic kidney disease in type 1 diabetes. The award funds research integrating single-cell RNA sequencing, spatial transcriptomics, and metabolomics to map cellular sources of adenine, an...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Veterans Medical Research Foundation of San Diego $383,098 on September 2, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The recipient will conduct research into kidney tubule dysfunction in APOL1-associated chronic kidney disease, with focus on developing and validating tubular biomarkers that capture kidney functions—nutrient reabsorption and toxin...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Illinois $160,575 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant K01DK147658). The award funds a three-year study of Medicaid alternative payment model (APM) implementation and evidence-based practice adoption in federally qualified health centers (FQHCs) to improve diabetes outcomes. The research addresses how FQHCs, which...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Beckman Research Institute of the City of Hope $8.445 million on May 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify circulating extracellular vesicles as biomarkers for early detection of type 1 diabetes. The recipient will isolate circulating extracellular vesicles from plasma, perform proteomic and RNA sequencing analysis on the vesicles, and conduct...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Broad Institute, Inc. $1,647,485 on September 19, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct massive-scale genomic risk assessment across monogenic and common forms of diabetes. The award will support analysis of the largest dataset of rare variation linked to diabetes phenotyping, comprising more than 1.1 million participants (33 percent...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Albert Einstein College of Medicine $887,696 on February 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to profile plasma proteome across 2,300 individuals from the Hispanic Community Health Study/Study of Latinos (SOL) cohort, including repeated proteome measures in 1,000 individuals over approximately six years, using Olink Explore HT technology to measure...
Amdx Prognostx Inc. received a $791,145 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases within the Department of Health and Human Services. The award falls under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), which promotes biomedical research to improve understanding and treatment of diabetes, digestive, and kidney diseases. Under this award, Amdx Prognostx will develop an enzyme-linked immunosorbent assay (ELISA) test to identify patients with prediabetes or early Type 2 diabetes who are at high risk of rapidly progressing to chronic kidney disease. The test analyzes a novel biomarker that reflects critical pathophysiological processes leading to accelerated CKD progression in this patient population. In the initial one-year project period ending July 2022, the company will further develop and validate the prototype assay using longitudinal human samples to evaluate its ability to distinguish between prediabetic patients who did or did not subsequently develop CKD and diabetes. The test aims to enable earlier clinical intervention and management of high-risk individuals, with the long-term goals of FDA approval and coverage by the Centers for Medicare and Medicaid Services.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $263.7k | 7/22/21 | ||
| Not listed | $263.7k | 7/22/21 |