Project Grant R21DK143419
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $478,011 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Trustees of Boston University's Medical Campus. This 2-year grant, with a period of performance from September 2025 to August 2027, will fund the development of a novel deep learning framework to automate the analysis of kidney transmission electron microscopy (TEM) images. The goal is to...
- This Project Grant award of $306,873 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to develop an AI-driven automated system for accurately generating Banff lesion scores from kidney biopsy slides. The project, titled "BANFF-AID: BANFF Automated Nephrology Feature Framework - Artificial Intelligence Diagnosis", will create custom AI models to extract...
- This Project Grant award for $124,284 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) will support research conducted by Weill Medical College of Cornell University. The key objectives are to: Develop a super-resolution deep learning framework to generate high-resolution 3D MRI volumes for enhanced monitoring of Autosomal Dominant Polycystic Kidney Disease (ADPKD), incorporating multiple...
- This Project Grant award of $404,883 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop integrated spatial transcriptomics and proteomics technologies for studying kidney disease. The project, titled "Submicron-Resolution Integrated Spatial Transcriptomics and Proteomics for Studying Kidney Disease", will optimize a high-resolution spatial...
- This federal Project Grant award of $304,993 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Immunowork LLC, located in Monrovia, CA. The award supports a research project to quantify peripheral blood antigen-specific memory B cells as a new biomarker in patients with PLA2R-associated membranous nephropathy, a common form of nephrotic syndrome. The goal...
- This $305,844 Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will support an AI-based image phenotyping repository core at Weill Medical College of Cornell University. The project aims to facilitate translational and basic research on polycystic kidney disease (PKD) by providing access to accurate, comprehensive measurements of PKD features visible on clinical imaging (MRI, CT). The core will fully label and store research...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $199,999 to the University of Florida to develop innovative artificial intelligence (AI)-based methods to support the discovery of potent, orally available small-molecule heparanase inhibitors. The goal is to evaluate these novel heparanase inhibitors in murine models as a...
- This $128,286 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the mechanisms of renal lipotoxicity and its contribution to the development of chronic kidney disease (CKD). The principal investigator will investigate the protective role of the FAF2 gene knockout in mitigating palmitate-induced lipotoxicity in...
- This federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $306,867 award to Dupage Medical Technology Inc. supports the development of a new drug to treat ischemia-reperfusion injury associated with kidney transplantation. The project aims to develop a therapy that can reduce inflammation and thrombosis without causing excessive...
- This federal Project Grant award in the amount of $1,695,959.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research to evaluate the use of gadolinium-free kidney functional magnetic resonance imaging (MRI) as a non-invasive method to identify high-risk phenotypes in patients with chronic kidney disease (CKD). The key products and...
This Project Grant award, titled "Revolutionizing Renal Histopathology: Integrating Multiplexed Immunofluorescence and ML/AI Image-Based Biomarkers for Precision Diagnosis and Patient Stratification", is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $464,750 award aims to develop an advanced imaging and analysis platform for renal diagnostics, integrating multiplexed immunofluorescence imaging and machine learning/artificial intelligence techniques to generate quantitative, multi-variate image-based biomarkers. This innovative approach is designed to enhance diagnostic precision and patient stratification for kidney diseases, which affect hundreds of millions globally. The award was granted to President and Fellows of Harvard College, doing business as Harvard Medical School, a prominent academic research institution, and will be performed in Massachusetts. The project period runs from September 2025 to August 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $464.8k | 9/5/25 |