Project Grant R01DK140545
Award Date 9/19/25
Completion Date 5/31/30
Dollars Obligated $882K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
- This federal Project Grant award of $1,620,238 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award will fund a research project at the University of North Carolina at Chapel Hill (UNC-CH) to detect regulatory variants and elements at type 2 diabetes genetic association signals across multiple tissues, including pancreatic islets, adipose, skeletal...
- This $2,782,476 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) supports research to determine the molecular mechanisms underlying pancreatic beta cell response to metabolic stress, a key factor in the development of type 2 diabetes. The 4-year project aims to leverage in vitro human beta cell models, single-cell transcriptomic analyses, and targeted drug screening to delineate the dynamic chromatin and transcriptomic changes that...
- This $223,176 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to characterize the role of apolipoprotein L1 (APOL1) copy number variations (CNVs) in kidney disease susceptibility among African Americans. The research, conducted by Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, MA, aims to: 1) develop a computational...
- This federal Project Grant award in the amount of $1,428,186.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts. The project aims to investigate the role of CYP4F enzymes in regulating N-acyl amino acid signaling in humans, which has implications for understanding the early...
- This Project Grant award of $248,915 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to unravel the role of epigenetics and cytokines in type 2 diabetes among African-ancestry populations in the U.S. and Europe. The research aims to identify causal associations between DNA methylation, circulating cytokines, and diabetes risk in these populations...
- This $659,358 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research at Beth Israel Deaconess Medical Center, Inc. (Bidmc) investigating the genetic and biological mechanisms underlying kidney disease associated with APOL1 risk variants, particularly focused on the relationship between APOL1 gene dose and kidney...
- This $291,949 Project Grant was awarded on September 15, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant was awarded to Biosettia Inc. (UEI: GZM5S2UYEGD2) located in San Diego, CA to support research aimed at using deep sequencing to measure variants of the endogenous retrovirus (ERV) GAG gene as potential biomarkers for type 1 diabetes. The project seeks...
- The federal Project Grant award of $731,071 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to address the challenges preventing the provision of guideline-recommended diabetes care in the United States. The overarching goals are to: Describe differences in diabetes care receipt across individual, neighborhood, and insurance characteristics. Examine differences in...
- This Project Grant award of $277,089, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to improve understanding of the genetic drivers of nephrotic syndrome (NS) in order to guide clinical management and develop targeted therapies. The research, conducted by The Children's Hospital Corporation (dba Boston Children's Hospital), will investigate the...
- This Project Grant award of $787,367 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program, will support a multidisciplinary research project to map the gene regulatory architecture of pancreatic islet-specific cell types and their role in diabetes. The primary objectives are to: 1) Create a comprehensive map of islet cell types by integrating single-cell gene expression and...