Project Grant R35GM165541
Award Date 8/10/26
Completion Date 5/31/31
Dollars Obligated $394K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Boston, MA 02114, USA
Similar Awards
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $453,750 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate novel molecular mechanisms of nutrient signaling networks in plants, specifically exploring how Target-of-Rapamycin (TOR) signaling promotes growth and development while repressing stress-innate immunity, and to characterize calcium-sensor protein kinases...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $443,090 under the Biomedical Research and Research Training program (CFDA 93.859) on September 1, 2026. The award funds a five-year research program investigating the mechanisms of perioperative neurocognitive disorder, a neurotoxic condition arising from anesthesia and surgery that is characterized by declines in memory, attention, and executive...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $444,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop secreted genetically encoded fluorescent biosensors for in vivo extracellular imaging. The project will create a toolkit of biosensors across four research areas: imaging extracellular matrix structures by conjugating fluorescent proteins to lectins and...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $453,750 under the Biomedical Research and Research Training program (CFDA 93.859) on August 1, 2026, through Project Grant R35GM165865. The award funds research investigating how mitochondrial metabolism regulates species-specific developmental rates in mammalian embryos. The research program uses an in vitro system that recapitulates the two- to threefold difference in...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $635,367 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate molecular mechanisms of cell division and cell signaling. The research addresses how micron-scale microtubule structures organize as signaling scaffolds in cell division and Hedgehog signal transduction. In the cell-division strand, the work focuses on...
- The National Institute of General Medical Sciences (NIGMS), part of the Department of Health and Human Services National Institutes of Health, awarded $416,815 to Dana-Farber Cancer Institute, Inc. on August 3, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support mechanistic research on metabolite signaling in tissue resident macrophages. The funded research aims to identify how metabolites regulate macrophage function across diverse tissue environments...
- The National Institute on Aging awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $463,000 under the Aging Research program (CFDA 93.866) on May 1, 2026, to support research investigating chromatin mechanisms of cytoplasmic chromatin fragments during senescence and aging. The research examines how chromatin fragments transit from the nucleus to the cytoplasm in senescent and aged cells, activating the cGAS-STING immune pathway and driving chronic...
- The National Institute of Neurological Disorders and Stroke awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $1.854 million on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into compartmentalized reactive oxygen species (ROS) sensing in the brain, specifically investigating how neurons balance mitochondrial energy production with ROS control....
- This Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program provides $819,980.00 in funding to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct research on elucidating sex differences in melanoma tumorigenesis. The 3-year research project, beginning on August 15, 2024 and ending on August 14, 2027, aims to advance the understanding and treatment of this complex...
- The National Institute of General Medical Sciences awarded the University of Massachusetts $2.35 million on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate non-specific electrostatic interactions of biological macromolecules in physiological and pathological processes. The project examines how highly charged polycationic and polyanionic biomacromolecules — including heparin, neutrophil extracellular traps, and other polymeric species —...