Project Grant R34AR084192

Award Date 8/15/24
Completion Date 7/31/26
Dollars Obligated $298K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Cleveland, OH 44109, USA
Similar Awards
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $206,016 to support research into systemic juvenile idiopathic arthritis-related lung disease (SJIA-LD). The objectives are to define the clinical characteristics and progression of SJIA-LD, validate biomarkers of disease activity and lung injury, and utilize patient-reported...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $212,574 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Seattle Children's Hospital, operating as the Seattle Children's Research Institute. The grant will fund a 5-year mentorship program led by Dr. Shaun Jackson to train the next generation of researchers in pediatric autoimmunity. The program will provide structured training, individualized...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will provide $401,433 from September 2023 to August 2025 to support research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The research aims to investigate the role of protein O-GlcNAcylation in regulating keratinocyte function and its impact on skin...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to assess the use of Spatial Frequency Domain Imaging (SFDI) as an objective measure of skin changes in systemic sclerosis (scleroderma). The $173,719 award to Trustees of Boston University will prospectively evaluate SFDI's ability to track disease progression over 12 months, comparing its...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) provides $408,031 to support a comparative effectiveness study of current treatments for children with chronic nonbacterial osteomyelitis (CNO). The study aims to determine the impact of prolonged non-steroidal anti-inflammatory drug (NSAID) treatment on reducing disease flares, as well as...
This federal Project Grant award, valued at $194,700.00 and funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to characterize the biobehavioral basis of cognitive dysfunction in childhood-onset systemic lupus erythematosus (cSLE). The research aims to investigate functional central nervous system properties, white matter microstructure, and...
The federal Project Grant award K23AR084424, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to identify and reduce non-adherence to hydroxychloroquine (HCQ) medication in adolescents with pediatric systemic lupus erythematosus (PSLE). The $317,304 award to Duke University will be used to: 1) define an HCQ concentration cutoff as an objective...
This federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to study precision monitoring of treatment response in early psoriatic arthritis. The $465,008 award to New York University School of Medicine, with sub-awards to the University of Washington and Jackson Laboratory, will integrate at-home RNA microsampling and smartphone-based...
This Project Grant award of $177,650 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award will fund an observational study to determine if interleukin-1 (IL-1) inhibition therapy can reduce flare activity and new heterotopic ossification (abnormal bone formation) in patients with the rare disease fibrodysplasia ossificans progressiva (FOP). Key...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will provide $260,375 to the University of California, Los Angeles (UCLA) to develop and validate a saliva-based assay for the early detection of Sjögren's disease (SJD) and autoimmune-sicca syndrome (AI-sicca). The key products and services to be delivered include: Acquiring and characterizing clinical cohorts of SJD, AI-sicca,...

This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund research to develop patient-driven outcome measures and an N-of-1 clinical trial design to evaluate therapies for Childhood Sjogren's Disease (CSD), a rare autoimmune condition affecting children. The $297,940 award, effective August 15, 2024 through July 31, 2026, will be administered by Case Western Reserve University. The project aims to create consensus on CSD flare criteria, develop patient-important outcome measures, and prepare a protocol for N-of-1 trials to evaluate CSD therapies. This work will establish a collaborative network of pediatric rheumatology centers to support future CSD studies, addressing the lack of pediatric-specific clinical trials for this disease.

Generated 6/10/25, 6:03 AM