This federal Project Grant award from the National Institutes of Health (NIH), under the Research Infrastructure Programs (CFDA 93.351), supports the development of a novel mouse model system for targeted trimming of disease susceptibility loci. The goal is to streamline the identification of causative genes within large susceptibility loci, enabling more efficient advancement of disease mechanism studies and therapeutic development. The $261,017 award, with a project period from May 1, 2025 to April 30, 2027, will fund the generation of two new mouse lines that can be crossed to reconstitute the required components for this targeted trimming approach. This technology aims to provide a reliable, time- and cost-effective means of mapping causative mutations within complex genetic regions associated with various diseases and traits. The grant was awarded to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., a nonprofit organization with extensive experience in supporting federal medical research initiatives.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $261.0k | 4/24/25 |