Project Grant R21EY037057
Award Date 9/1/25
Completion Date 8/31/27
Dollars Obligated $448K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
- The University of Massachusetts Boston received a $435,052 project grant from the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) to conduct research on the molecular mechanisms that control the spatially precise expression patterns of photoreceptor subtypes for color vision. The long-term goal is to use the Drosophila melanogaster retina as a model to decipher the cis-regulatory mechanisms and identify conserved trans-acting factors that specify...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $448,250 to The Research Foundation for the State University of New York (Upstate Medical Center) to conduct research on the "Composition and Function of Optix-Cofactor Transcription Complexes in the Eye." The research aims to characterize the Optix protein complexes that regulate eye development and function, with the goal of understanding their specific roles in controlling gene...
- This $448,250 project grant was awarded by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) to The Research Foundation For The State University Of New York, operating as Upstate Medical Center. The grant will support an investigation into the transcriptional dynamics of the CRX homeodomain transcription factor and its role in regulating photoreceptor gene expression. The research aims to characterize CRX mobility modes, chromatin binding dynamics,...
- This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) is supporting research at New York University (NYU) to investigate the mechanism of corneal lens development in the Drosophila model organism. The $142,749 award, spanning September 2025 to August 2027, aims to use genetic, microscopy, and transcriptomic approaches to study the role of the polysaccharide chitin and the central and lattice cells of the fly corneal lens in...
- This $148,568 Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), supports research at Emory University to investigate the role of scleral fibroblasts in refractive development and myopia. The primary objectives are to: 1) Identify characteristics of scleral fibroblasts in mouse eyes that undergo normal refractive development versus those exposed to myopic stimuli, and 2) Determine the role of retinoic acid signaling in driving...
- The National Eye Institute (NEI) awarded a $437,310 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Rochester to conduct research on the molecular and physiological mechanisms of inner retinal remodeling in retinal degeneration. The research aims to elucidate the mechanisms behind genetic, morphological, and physiological changes in retinal ganglion cells that lead to decreased signal-to-noise ratio and corruption of retinal circuits, with the...
- The University of Utah has been awarded a $423,500 Project Grant from the National Eye Institute (NEI) under the NIH's Vision Research program (CFDA 93.867) to study the role of microglia in the development of the optic stalk during early eye formation. The research aims to determine whether microglia, the resident immune cells of the central nervous system, participate in apoptotic cell elimination and tissue remodeling processes that are critical for normal closure of the optic fissure....
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $144,200 Project Grant to Pennsylvania State University's Milton S. Hershey Medical Center. The grant, effective June 1, 2025 through November 30, 2027, will fund research to characterize the molecular mechanisms underlying increased levels of the protein REDD1 in the retina due to diabetes, and explore alternative intervention strategies for preventing retinal complications caused by...
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $431,750 Project Grant to the University of Louisville to study the role of neurexin proteins in retinal structure and function. The grant, effective from September 1, 2025 to August 31, 2027, aims to 1) determine the function of three neurexin genes and their isoform-specific expression patterns within the retina, and 2) characterize the cell-type-specific expression of neurexin isoforms...
- This is a Project Grant award from the National Eye Institute (NEI), part of the National Institutes of Health (NIH), under the Vision Research program (CFDA 93.867). The $451,000 award supports research by the University of Texas Southwestern Medical Center to investigate the role of the FIC enzyme in regulating the unfolded protein response (UPR) in the mammalian retina. Specifically, the project aims to determine if FIC-mediated modification of the BIP protein can modulate UPR activation,...