This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research to establish a novel zebrafish model of syndromic craniosynostosis. The $313,000 award to Emory University will enable comprehensive phenotypic, mechanistic, and genetic analyses of the craniosynostosis mutant zebrafish to better understand the underlying pathological mechanisms. The research aims to identify...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $315,000 to the University of California, Los Angeles (UCLA) from July 2025 to July 2027. The funding supports research to investigate the role of distinct neural crest cell populations in the development and maintenance of cranial sutures, and explore potential biological therapeutics to resolve premature suture fusion...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $1,608,956 to The Regents of the University of California, operating as Lawrence Berkeley National Laboratory, to conduct research on human midface development and genetic factors underlying craniofacial birth defects. The key activities include: Generating a single-cell multimodal atlas of human craniofacial...
The National Institute of Dental and Craniofacial Research (NIDCR) has awarded a $148,176 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Regents of the University of California, Berkeley. The funding will support research to uncover novel gene regulatory networks underlying craniofacial development and specialization in pupfish species. The project aims to leverage the unique evolutionary model of Cyprinodon pupfishes on San Salvador Island to...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,325,889 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Southern California on September 19, 2024. This grant, titled "Regulating Skeletal Connectivity in Craniofacial Development and Disease," will support a comprehensive and forward-thinking research program led by Dr. Amy Merrill that investigates the craniofacial skeleton as a multi-tissue...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $550,810 Project Grant (CFDA 93.121 - Oral Diseases and Disorders Research) to Vanderbilt University Medical Center to create the Human Craniosynostosis Atlas (HUCA). The project aims to standardize data acquisition protocols and establish a public repository of comprehensive CT, MRI, and genomic data for characterizing all types of craniosynostosis, a premature fusion of the cranial sutures affecting 1 in 2,000...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $493,458 to Childrens Hospital Medical Center in Cincinnati, Ohio to conduct research on the role of ARID1 proteins in craniofacial neural crest cell development. The project aims to investigate how ARID1A and ARID1B subunits of the BAF chromatin remodeling complex regulate multipotency,...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $1,867,823 to support research on the genomic and developmental mechanisms underlying a congenital craniofacial disorder called frontonasal dysplasia (FND). The research aims to study how structural variations in the genome can disrupt the regulation of neighboring genes, such as SIX2 and SIX3, and lead to craniofacial...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $919,059 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the role of the ESCRT (Endosomal Sorting Complexes Required for Transport) machinery in regulating craniofacial morphogenesis. The award period runs from September 16, 2024 to August 31, 2029. The research aims...
This federal Project Grant award, valued at $294,000 and spanning September 2024 to September 2026, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The grant supports research to understand the mechanisms of craniofacial cartilage differentiation from human neural crest stem cells, with the goal of developing tissue engineering approaches to repair birth defects and injuries to the head and...