This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $550,810 to Vanderbilt University Medical Center (VUMC) to create the Human Craniosynostosis Atlas (HUCA). HUCA aims to establish a public repository of standardized genomic and neuroimaging data on craniosynostosis, a premature fusion of the cranial sutures affecting approximately 1 in 2,000 infants annually. The project will collect CT, MRI, and whole genome sequencing data from infants with craniosynostosis and their parents, and transfer this data to the existing NIDCR-supported FaceBase 3 biorepository. By creating this comprehensive multi-modal dataset, the project seeks to improve the fundamental understanding and characterization of craniosynostosis, with the goal of enabling clinicians to better predict and optimize treatment outcomes. The award period runs from Sep 19, 2024 to Aug 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 10/25/24 | ||
| Not listed | $275.4k | 9/19/24 | ||
| Not listed | $275.4k | 9/19/24 |