Project Grant R21AR083023
Award Date
8/15/24
Completion Date
7/31/26
Dollars Obligated
$216K
Awardee
Baylor University (C6T9BYG5EYX5)
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Waco, TX 76798, USA
Similar Awards
This Project Grant award, valued at $248,724.00, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award will support research at the University of Alabama at Birmingham (UAB) to investigate the role of cellular senescence in skeletal muscle loss and dysfunction. The key objectives are to (1) develop a translational research program on mechanisms underlying...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is funding research to explore the role of mitochondrial permeability transition (MPT) in skeletal muscle dysfunction and inflammation in sepsis. The $193,188 award, which runs from Sep 1, 2024 to Aug 31, 2026, will support experiments testing the hypothesis that skeletal muscle-specific knockout of...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $458,907 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The University of Kentucky Research Foundation. The 5-year grant (2/1/2025 - 1/31/2030) will fund research to determine if the gut microbiome of exercise-trained mice can attenuate skeletal muscle atrophy, and if administering specific probiotic bacteria or microbial-derived metabolites can...
This $820,142 federal Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 "Arthritis, Musculoskeletal and Skin Diseases Research" will fund research to investigate the impact of early-life physical inactivity on adult muscle quality, function, and frailty development in mice. The primary objectives are to: 1) examine the effect of varying levels of early-life physical inactivity on muscle quality and function in...
This $146,816 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) will support research training and investigation into the role of the muscle circadian clock as a modifier of cancer cachexia. The key objectives are to: 1) Define the stage of cancer cachexia at which the muscle clock is disrupted and examine the relationship between clock disruption...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $626,483 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to the Icahn School of Medicine at Mount Sinai to study the role of netrin signaling in regulating muscle stem cell quiescence and activation. The 2-year project aims to determine how netrin-1, an axonal chemoattractant, influences muscle stem cell morphology, quiescence, and the transition to activation using a...
This $557,357 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund research at the University of Wisconsin-Madison to investigate the role of HOX-expressing interstitial cells in skeletal muscle growth, homeostasis, and regeneration. The project aims to interrogate the lineage potential and functional mechanisms of this novel cell population,...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has awarded a $383,570 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to Trustees of Indiana University, doing business as Indiana University Indianapolis. The grant, titled "Delineating the Contribution of Muscle Wasting to Tumor Progression," aims to better understand the relationship between skeletal muscle wasting and tumor progression in cancer patients. The...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) for $673,650 aims to evaluate the hypothesis that inflamed adipose tissue contributes to blunted exercise response in skeletal muscle of older adults. The research objectives are to: Determine how adipose tissue influences skeletal muscle function and anabolic response to exercise in older adults using in vivo imaging and molecular phenotyping. Identify the molecular pathways by which abdominal...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to investigate the functional roles of microRNA-320 (miR-320) in skeletal muscle. The $374,204 grant awarded to The Leland Stanford Junior University will be used to: 1) characterize the phenotype of miR-320 knockout mice, examining muscle size, fiber type, and contractile force; 2)...