The University Of Kentucky Research Foundation was awarded a $458,907 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will fund research to investigate the role of the gut microbiome in treating skeletal muscle atrophy. Specifically, the project aims to determine if cecal microbial transplants from exercise-trained mice can attenuate muscle atrophy, and whether administration of specific probiotic bacteria or microbial-derived metabolites can produce a similar effect. The research seeks to develop a novel therapeutic strategy to treat muscle atrophy, which often results from disease, injury, or aging. The project will run from February 1, 2025 through January 31, 2030.
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