Project Grant R21AR083774
Award Date
9/20/23
Completion Date
8/31/25
Dollars Obligated
$384K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Indianapolis, IN 46202, USA
Similar Awards
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a 5-year, $732,272 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to the Trustees of Indiana University (Indiana University Indianapolis) to establish the Indiana Center for Musculoskeletal Health (ICMH) Resource Cores. The goal is to promote advancements in musculoskeletal research through understanding muscle/bone interactions, mechanobiology, and the...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $526,174 to Duke University to engineer heterocellular human skeletal muscle tissues. The goal is to recreate and study the native stem cell niche function of healthy skeletal muscle, which is critical for its regenerative capacity. By incorporating capillary networks and functional...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $575,021 Project Grant (CFDA 93.846) to The Johns Hopkins University on September 1, 2024. The grant supports research to (i) develop and validate a model to predict cancer risk in patients with idiopathic inflammatory myopathies (IIM), and (ii) determine how the emergence and elimination of cancer impacts clinical outcomes for IIM patients. The research aims to enable improved clinical decision-making...
This $146,816 Project Grant was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant, running from July 1, 2025 to June 30, 2028, will support research to investigate the role of the muscle circadian clock in cancer cachexia, a debilitating condition affecting up to 80% of cancer patients. The research aims to define how disruptions in the muscle clock...
This federal Project Grant award, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research into the functional roles of microRNA-320 in skeletal muscle. The $374,204 award to The Leland Stanford Junior University will be used to characterize the phenotype of a muscle-specific microRNA-320 knockout mouse model, investigate the underlying molecular...
This Project Grant award of $248,724.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to investigate the role of cellular senescence in skeletal muscle loss and dysfunction. The primary objectives are to: 1) obtain experimental skills and career training to develop a translational research program on mechanisms underlying skeletal muscle wasting,...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund research to investigate a novel set of Hox-expressing interstitial cells and their potential role in muscle growth, homeostasis, and regeneration. The $557,357 award to the University of Wisconsin-Madison will support a 5-year research project that aims to interrogate the lineage potential...
This federal Project Grant award, R01AR084282, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The $458,907 award will fund research to determine if the gut microbiome can be leveraged as a novel therapeutic strategy to treat skeletal muscle atrophy. The key products and services to be delivered include: 1) Evaluating if cecal microbial transplant from...
This $193,188 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to investigate the role of mitochondrial permeability transition (MPT) in skeletal muscle dysfunction and systemic inflammation in sepsis. The central hypothesis is that knockout of the MPT-promoting protein cyclophilin D in skeletal muscle will attenuate both muscle...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the federal Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $473,377 to the University of California, Irvine to conduct research aimed at improving skeletal muscle regeneration through modulation of the stem cell niche. The key focus is on understanding how human pluripotent stem cells (hPSCs) can be directed to mature into functional muscle...