Project Grant R21AI190721
Award Date
7/1/25
Completion Date
6/30/27
Dollars Obligated
$424K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Minnesota, USA
Similar Awards
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $138,051 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Regents of the University of Minnesota. The grant supports research to understand the role of thymic B cells in regulating immune tolerance and autoimmune diseases. The research aims to investigate how type-III interferon-driven licensing of thymic B cells impacts the development of T regulatory cells that become...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,286,273.00 to The Trustees of Columbia University in the City of New York to conduct preclinical studies on inducing liver transplant tolerance. The research aims to develop clinically applicable protocols for tolerance induction in living and deceased donor liver transplantation, as well as to define the...
This Project Grant award, with a total funding amount of $210,867, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The funding will support research conducted by Drexel University to develop a cell-based therapy for generating donor-specific immune tolerance in kidney transplant recipients. The key products and services to be delivered under this grant include: Engineering...
This federal Project Grant award, R21AI182549, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $246,623 grant will fund research by New York University School of Medicine to study the molecular control of tolerogenic dendritic cell function. The research aims to pinpoint the dendritic cell subset responsible for regulating immune tolerance, characterize the molecular basis of...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), is providing $162,512 to the Regents of the University of Minnesota to investigate the factors that support the expansion and function of long-lived effector CD8 T cells within the memory compartment. The key objectives are to determine what pro-inflammatory cytokines and other factors promote the formation and...
This federal Project Grant award of $417,984 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research conducted by the Scripps Research Institute to identify small molecule compounds that can selectively induce the differentiation of functional regulatory T cells (Tregs). The research aims to address challenges in expanding Treg populations without causing unintended...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $553,342 to the Regents of the University of Minnesota to conduct research on CD4+ T cell response to food antigens. The research aims to understand how exposure to food peptides bound to major histocompatibility complex class II (MHCII) molecules leads to the formation of regulatory T (Treg) cells and a...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,648,086 to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania, to conduct research on immune repertoire remodeling following B cell-targeted CAR T cells for the induction of renal allograft tolerance in non-human primates. The goal is to...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $224,070 to the Regents of the University of Minnesota to conduct research on stromal-immune cell interactions that promote autoimmune valvular carditis. The research aims to investigate how immune cells and stromal cells, such as fibroblasts and endothelial cells, communicate to perpetuate inflammation and fibrosis in...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $231,131 to Duquesne University to develop and evaluate injectable 3D-clustered human fibroblastic reticular cells (clFRCs) for expanding regulatory T cells (Tregs) in allograft transplant applications. The key products to be delivered include: Optimized clFRC prototypes capable of generating Tregs in vitro by tuning...