This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,648,086 to support research on inducing immune tolerance in kidney transplant recipients. The award, with a start date of May 13, 2025 and an end date of April 30, 2030, will fund preclinical trials in a non-human primate model to evaluate the use of CD20-targeted CAR T cell therapy for depleting B cells and modifying the immune repertoire to promote transplant tolerance. The project aims to develop new therapeutic approaches and technologies to enable clinical translation of this strategy for kidney transplant patients. The research will be conducted by the Trustees of the University of Pennsylvania, a prestigious private research university and academic medical center.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1.6m | 5/13/25 |