Project Grant R21AI190485
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $451,000 to the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 15, 2025, with completion scheduled for July 31, 2027. This Project Grant supports the development and application of high-resolution phage immunoprecipitation sequencing (PhIP-Seq) arrays designed to comprehensively evaluate antibody responses to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,351,924 Project Grant to The Regents of the University of California, San Francisco on August 11, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, which extends through July 31, 2030, aims to characterize interactions between human and vector behaviors to enhance malaria control interventions in Uganda. The primary deliverable involves...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of California, San Francisco a Project Grant of $895,740 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 2, 2026 through January 31, 2031. This award supports research focused on characterizing CD4 T cells targeting liver and blood stage malaria epitopes to advance malaria vaccine development. The research will identify hundreds...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Regents of the University of California, San Francisco a Project Grant totaling $787,837 under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning April 10, 2026, with a completion date of March 31, 2031. This five-year initiative will develop and validate computational and statistical tools designed to assess the risk that diseases with episodic transmission...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of California, Irvine $823,548 on May 11, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop antimalarial and antibabesial clinical candidates based on leelamine-derived isonitriles. The research focuses on creating dual-acting therapeutic agents targeting Plasmodium falciparum and Babesia species, the causative agents of human...
- Federal Project Grant Award Summary The University of South Florida received a Project Grant award of $203,060 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 1, 2026 through March 31, 2028. This research initiative focuses on investigating the ecology of Plasmodium malariae transmission in Cameroon, specifically addressing the patchy distribution and seasonal variations of this...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Medical College of Wisconsin, Inc. a Project Grant totaling $157,884 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period of December 26, 2025 through June 30, 2029. This research grant supports investigator-initiated biomedical research aimed at advancing understanding of infectious disease mechanisms and improving vector control strategies against malaria...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Leland Stanford Junior University a Project Grant totaling $789,442 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 17, 2025, with a completion date of June 30, 2030. This research initiative employs multi-omics approaches—including single-cell proteomic and transcriptomic analyses—to investigate how the immune system adapts to repeated Plasmodium...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $107,542 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2027. The award supports investigator-initiated biomedical research examining the differential sorting and trafficking mechanisms of Plasmodium falciparum secreted proteins, with particular focus on how...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of California, Los Angeles a $736,920 Project Grant effective July 22, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic scientific research on the structure, assembly, and functional mechanisms of the flagellum in Trypanosoma brucei, a parasitic protozoan responsible for African trypanosomiasis (sleeping sickness). The research will...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Regents of the University of California, San Francisco a $246,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective May 1, 2026, with completion targeted for April 30, 2028. The project, titled "Malaria Importation and the Role of Agriculture in Local Transmission in Eswatini (MIRA)," will deliver advanced parasitological research services and genomic analysis to improve malaria case classification and identify drivers of residual transmission in endemic regions. Specifically, the research will leverage high-resolution genomic sequencing and analytical methods to quantify the contribution of imported malaria infections—particularly those carrying antimalarial drug resistance markers—among agricultural populations to ongoing transmission dynamics. The deliverables will include improved epidemiological case classification models utilizing parasite genomic data collected from existing studies conducted in Eswatini between 2012-2017 and new 2023 samples, complemented by contemporary genomic data from Mozambique to assess cross-border transmission connectivity. Research outputs will characterize transmission patterns and antimalarial drug resistance mutation profiles in relation to imported infections within vulnerable agricultural populations, addressing a critical knowledge gap in malaria elimination efforts by distinguishing imported from locally-acquired infections—a distinction that epidemiological data alone cannot establish.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $246.0k | 5/1/26 |