Project Grant R01AI190410
- This $451,000 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support the development of a comprehensive, high-resolution array to analyze antibody responses to variant Plasmodium falciparum antigens in populations naturally exposed to malaria. The research team at the University of California, San Francisco will leverage advanced bioinformatic and laboratory methods to create...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $214,160 to The Regents of the University of California, San Francisco (UCSF) to pilot the integration of nutritional interventions with the existing Seasonal Malaria Chemoprevention (SMC) platform in Burkina Faso. The goal is to evaluate how the SMC platform can be leveraged to deliver co-interventions that may augment the efficacy of SMC...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), is funding research to develop new tools and technologies for vector control of the Aedes aegypti mosquito, an important disease vector. The key focus is on evaluating conditional and sex-specific lethal systems that can restrict lethal transgene expression and reduce the fitness load on mosquito populations, as...
- This Project Grant award of $856,202 was provided by the National Institute of Allergy and Infectious Diseases (NIAID), which oversees the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program. The award will fund a 5-year study led by researchers at the University of California, San Francisco (UCSF) to investigate the role of IL-10 and IFN signaling in controlling the HIV reservoir and achieving functional HIV cure. The project aims to determine if enhancing IL-10 and...
- The Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), will fund a cluster randomized trial of Intermittent Preventive Treatment of malaria in school-aged children (IPTsc) in high-burden African countries. The $1,126,029 award to the University of California, San Francisco will support the delivery of IPTsc using dihydroartemisinin-piperaquine (DP)...
- This Project Grant award of $366,845.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), will support the development and evaluation of portable experimental huts for global malaria vector control decision-making. The award will validate a low-cost, portable experimental hut tent (PEHT) system based on World Health Organization guidelines to expand the geographic coverage of...
- The University of California, San Diego (UCSD) was awarded a $3,194,992.00 Project Grant by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant, awarded on July 16, 2025, supports research to study the roles and regulation of tissue-resident CD8 T cells during a persistent viral infection. The research aims to investigate the mechanisms that allow immune cells to adapt and maintain a long-term...
- The Project Grant titled "Impact of Antimalarials on Parasite Selection Through the Mosquito Vector" is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $192,364 award, which runs from August 2025 to July 2030, supports research at Yale University to investigate the effect of antimalarial drugs taken by humans on the development of malaria parasites within mosquitoes. The...
- This $423,500 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to examine the role of invariant natural killer T (iNKT) cells in driving pathogenic T cell responses in experimental cerebral malaria. The research aims to determine how the T cell receptor (TCR) mechanosensing properties of iNKT cells shape the development of CD8 T cell-mediated pathology in Plasmodium infection. The grant...
- This Project Grant award of $1,553,810 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to evaluate a genomic surveillance approach for monitoring artemisinin resistance in Plasmodium falciparum malaria in Africa. The project aims to identify genetic mutations and altered biological functions associated with artemisinin resistance, which is a critical concern as resistance emerges...
The University of California, San Francisco (UCSF) was awarded a $675,962 Project Grant by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The purpose of the grant is to characterize the interaction between human and vector behaviors in order to enhance the impact of malaria control interventions in Uganda. The project will integrate rigorous human behavioral and entomological monitoring data to elucidate gaps in protection from existing vector control tools, such as long-lasting insecticide-treated bed nets (LLINs). This research aims to guide the planning of tailored malaria control strategies by linking clinical outcomes to specific interventions, addressing the recent stall and reversal in progress against malaria in sub-Saharan Africa. The project will be carried out at UCSF from August 2025 through July 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $315.4k | 8/12/25 | ||
| Not listed | $360.6k | 8/11/25 |