Project Grant R21AG097277
- This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) totaling $200,000 provides funding from March 2025 to January 2030 to evaluate the use of a machine learning algorithm-based implementation strategy for a comprehensive care management and care coordination (CCM/CC) intervention to improve HIV care continuum outcomes. The primary goal is to utilize a predictive algorithm developed by the community-based partner Comprehensive...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of new Bayesian causal structural discovery and reinforcement learning methods to investigate the effects of combination antiretroviral therapy (cART) regimens on viral suppression and depression outcomes for people living with HIV. The $145,299 award to The Johns Hopkins University will leverage...
- The Johns Hopkins Neurohiv Comorbidities Scholar Program (JH-NEUROPHYTES) is a $432,000 project grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) with a period of performance from May 15, 2025 to February 28, 2030. The purpose of this program is to significantly increase the persistence and career progression of undergraduates and master's level students to graduate-level training in neuroHIV or closely aligned research areas. The program will...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $793,247 to the University of North Carolina at Chapel Hill to conduct research aimed at improving the health of people living with HIV across the lifespan. The key products and services to be delivered include: Developing and implementing a data-driven algorithm to assign validated causes for hospitalizations among people with HIV, and using...
- This Project Grant award from the Department of Health and Human Services' National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support) provides $703,644 to the Icahn School of Medicine at Mount Sinai to investigate the drivers of accelerated aging in people living with HIV (PWH). The research aims to study the effects of HIV and antiretroviral therapy on epigenetic aging and clonal hematopoiesis, as well as examine the role of socio-behavioral factors and genetic predisposition in...
- The federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $439,180 to The Johns Hopkins University to investigate the role of dopaminergic neuron-glial interactions in the striatum in the context of HIV infection and substance use disorders. The research aims to deconvolute the complex interplay between HIV, methamphetamine use, and alterations in dopamine signaling pathways, which can contribute...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
- The Johns Hopkins University was awarded a $672,248 Project Grant from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research) to study sex-specific features of the HIV reservoir and immune responses across the female reproductive lifespan in a cohort of Ugandans living with HIV. The 5-year project, which began on September 15, 2025, aims to: 1) analyze the impact of pregnancy on HIV reservoir and immunity, 2) assess HIV reservoir and...
- This Project Grant award, totaling $1,243,071.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant will fund the development of a new collaborative eligibility platform by Groupware Technologies, LLC (UEI: E8T9F94UU7D4) to support the application, determination, recertification, and enrollment processes for the Ryan White HIV/AIDS Program (RWHAP). The platform aims to increase linkage to care and retention...
- This federal Project Grant award, provided by the Department of Health and Human Services National Institutes of Health (CFDA 93.310 Trans-NIH Research Support program), will support a mixed-methods research study to understand the interplay of social and physical environments, loneliness, and cognition among older people living with HIV. The $123,579 award, with a performance period from June 15, 2025 to March 31, 2030, will be administered by Northeastern University. The research aims to...
This Project Grant award, totaling $428,493, was provided by the U.S. Department of Health and Human Services' National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The grant was awarded to The Johns Hopkins University on September 5, 2025 to support a research project titled "Characterizing and Predicting Comorbidity Cascade Among Men and Women With and Without HIV by Harnessing Data from MWCCS and Electronic Medical Records." The key objectives of this project are to: 1) Establish an electronic health record registry nested within the MACS/WIHS Combined Cohort Study (MWCCS) to study comorbidity burden and cascade among people with and without HIV, and 2) Leverage the MWCCS cohort data and newly linked electronic health records to develop predictive models of the comorbidity cascade in these populations. This research aims to advance understanding of the aging and comorbidities experienced by people living with HIV, with the goal of informing clinical decision-making and care.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $428.5k | 9/5/25 |