This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, is focused on determining the relationship between rapid ethanol tolerance and sleep regulation in Drosophila (fruit fly) models. The $215,159 award, spanning September 1, 2024 to August 31, 2026, will support three key experiments: 1) mapping rapid ethanol tolerance in sleep circuitry, 2) investigating the labile and consolidated memory-like states of rapid ethanol tolerance and their association with conserved tolerance genes in the sleep circuitry, and 3) surveying the function of known sleep genes in rapid ethanol tolerance. The expected outcome is a genetic and circuit-level understanding of the connection between rapid ethanol tolerance and sleep regulation in Drosophila, which could provide insights into the relationship between alcohol addiction and sleep disturbances in humans.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $215.2k | 8/29/24 |