This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) grant, provides $574,808 to support a research project titled "Translational Genetic Analysis in Human and Mouse GWAS to Identify the Genomic Architecture of Alcohol Sensitivity and Tolerance." The primary awardee is Trustees of Indiana University, doing business as Indiana University Indianapolis. The project aims to identify genetic variants and genes associated with alcohol sensitivity and tolerance in both human populations and diversity outbred (DO) mice. Key activities include conducting genome-wide association studies (GWAS) in human populations, performing quantitative trait locus (QTL), expression QTL (eQTL), and gene expression-trait correlation analyses in DO mice, and employing a variant graph database to identify shared regulatory effects across mouse and human. The project also involves sub-awards to the University of California, San Diego and Middlebury College to support specific research tasks. The award period is from September 9, 2024, to June 30, 2029.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $574.8k | 9/9/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
10290S | University Of California, San Diego | Project Grant R01AA031176 | $37.5k | 10/16/24 | |
10279S | President And Fellows Of Middlebury College | Project Grant R01AA031176 | $251.9k | 10/1/24 |