This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, is focused on determining the relationship between rapid ethanol tolerance and sleep regulation in Drosophila (fruit fly) models. The $215,159 award, spanning September 1, 2024 to August 31, 2026, will support three key experiments: 1) mapping rapid ethanol tolerance in sleep circuitry, 2) investigating the labile and...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $537,587 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The University of Texas Southwestern Medical Center to conduct research on the metabolic consequences of liver inflammation on alcohol consumption and alcohol-associated liver disease (ALD). The key objectives are to identify the mechanisms by which the transcription factor IRF3 suppresses the expression and secretion of the metabolic regulator...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) provides $431,918 in funding to Bryant University for a research project focused on understanding the neural circuitry mechanisms underlying maladaptive reward memories related to alcohol addiction. The research aims to use the genetic tractability of the Drosophila melanogaster model organism to investigate how alcohol disrupts memory circuit activity and drives...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) grant, provides $574,808 to support a research project titled "Translational Genetic Analysis in Human and Mouse GWAS to Identify the Genomic Architecture of Alcohol Sensitivity and Tolerance." The primary awardee is Trustees of Indiana University, doing business as Indiana University Indianapolis. The project aims to identify genetic...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Illinois. The $293,128 grant, awarded on August 23, 2024, will fund a study examining the neural correlates of alcohol reward in social contexts using a hyperscanning EEG setup. The research aims to evaluate the neural mechanisms underlying the rewarding effects of alcohol in social settings and assess how individual and group-level factors...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) program, provides $499,442 in funding to The Regents of the University of California, San Francisco (UCSF) from August 20, 2024 through July 31, 2027. The award supports research to investigate the role of brain-derived neurotrophic factor (BDNF) signaling in the ventral hippocampus and its contribution to the acute anxiolytic and social...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $399,048 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Rochester Institute of Technology (RIT) to examine behavioral and electrophysiological cue reactivity in young adult binge drinkers. The study will compare responses to uni- and multisensory alcohol and neutral cues that vary in degree of realistic appearance, and explore the effects of multisensory congruence on cue responses. The project...
This federal Project Grant award of $1,135,243 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will support research to investigate changes in neural mechanisms associated with cognitive reappraisal and alcohol cue reactivity during early abstinence from alcohol use disorder (AUD) treatment. The research, conducted by the University of Colorado-Denver and involving sub-awards to Emory University and the University of Denver,...
The University of California Irvine was awarded a $412,125 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The grant funds a research project to comprehensively determine how alcohol consumption alters the metabolism of critical organs, which can contribute to alcohol-induced organ damage. The project will employ arteriovenous metabolomics to quantitatively measure the dynamic metabolic...
This federal Project Grant award of $581,869 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the CFDA 93.273 Alcohol Research Programs, will fund a human neuroscience study to investigate the role of glucocorticoid receptor (GR) antagonism in alcohol use disorder (AUD). The study will evaluate the effects of a selective GR antagonist, PT150, on behavioral, neuroendocrinological, and physiological responses to stress and alcohol in 34 participants. The research aims...