Project Grant R03NS106444

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $1,544,840 to Oregon Health & Science University (OHSU) to investigate the effect of post-concussive sleep disruption on glymphatic function in collegiate athletes. The key objectives are to: 1) define pre-morbid risk factors for post-concussive sleep-wake disturbance (SWD), 2) establish the combined effects of concussion...

The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $702,315 Project Grant (CFDA 93.173) to the University of California, Berkeley to evaluate the effects of high-intensity physical exercise training as a therapy to improve language, cognition, motor skills, and emotional well-being in individuals with post-stroke aphasia. The project will recruit 110 participants to compare the multi-faceted impacts of the high-intensity exercise intervention against a...

This Project Grant award from the National Institute on Disability, Independent Living, and Rehabilitation Research (CFDA 93.433) provides $1,499,997 to the University of Washington to evaluate the efficacy of a novel rehabilitation intervention called "Tools for Recovery and Clinical Care" (ON-TRACC) in improving quality of life and function for individuals experiencing persistent post-concussive symptoms following mild traumatic brain injury. The study will compare ON-TRACC to...

The Department of the Army Medical Command awarded a $4.7 million Project Grant to The Research Foundation for the State University of New York to support the research project "Exercise Reset for Concussion: Modifying the Buffalo Concussion Protocol for Application in a Military Environment" from September 2022 through September 2026. The grant was awarded under the Military Medical Research and Development program (CFDA 12.420), which supports biomedical research to improve military...

The National Institute of Child Health and Human Development (NICHD) awarded a $346,500 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Colorado-Denver to conduct a randomized clinical trial evaluating a multidimensional sleep health intervention for improving recovery outcomes among adolescents with concussions. The 2-year project aims to determine if the targeted sleep health intervention leads to faster symptom resolution, better sleep...

The National Institutes of Health's National Institute on Aging awarded a $2,366,184 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital, to support research into the mechanisms of circadian and synaptic dysfunction after repetitive mild traumatic brain injury. The three-year award, made on June 1, 2022 under the Aging Research program (CFDA 93.866), will fund work by Drs. Whalen and Lipton to define how interleukin-1 receptor 1-mediated...

This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,746,306 to Spirit Fit & Health, Inc. to develop and evaluate an evidence-based, stakeholder-informed digital platform for promoting physical activity and wellness among individuals with chronic brain injuries. The project aims to enhance Spirit Fit & Health's existing virtual fitness...

The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, awarded a $739,772 Project Grant to Cian, Inc. to develop a cilia biomarker kit for diagnosing and prognosticating traumatic brain injury (TBI) outcomes. The key products to be delivered through this 2-year grant are: 1) Developing specific monoclonal antibodies targeting two proteins expressed in cilia,...

This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $3,161,352 in funding to the University of Colorado-Denver to investigate the effects of aerobic exercise training on peripheral endothelial function and cerebrovascular function in adults of different ages and sexes. The 5-year research project will conduct a randomized controlled trial to assess changes in vascular function outcomes and analyze associated molecular biomarkers,...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $245,625 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to The Johns Hopkins University. The grant, titled "DELTA ECMO ABI STUDY (ASSESSING ACUTE BRAIN INJURY AFTER RAPID REDUCTION OF PACO2 UPON ECMO CANNULATION USING PORTABLE MRI AND BIOMARKERS)", aims to investigate the link between rapid changes in carbon dioxide levels and acute brain injury in...