This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, is funding the development of an innovative point-of-care device to quickly diagnose and monitor the severity of traumatic brain injury (TBI). The $332,122 award to Hemex Health Inc. will enable the creation of a portable, microchip-based platform that can rapidly detect and...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop and assess novel frameworks that can accurately predict functional outcomes at 6 months post-injury for patients with moderate-to-severe traumatic brain injury (TBI). The $389,813 award, with a period of performance from August 5, 2024 to July 31, 2026, will...
This $2,888,616 cooperative agreement award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support analytical validation of 7 emerging biomarkers for traumatic brain injury (TBI). The University of Pittsburgh, as the prime recipient, will partner with Morehouse School of Medicine, The Hospital for Sick Children, and the University of British Columbia as sub-awardees...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,855 to Mito-Biotherapeutics, Inc. aims to develop a novel fusion protein construct (NFP) that can cross the blood-brain barrier and deliver a therapeutic payload to repair mitochondrial DNA damage in neurons following traumatic brain injury (TBI). The proposed research program will verify the NFP's technical capability for complex navigation, and demonstrate its ability to...
This federal Project Grant award R01NS135081 for $677,014 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a novel non-invasive device for monitoring intracranial pressure (ICP) and cerebral blood flow in patients with traumatic brain injury (TBI). The key products to be developed under this 5-year grant include a speckle contrast optical...
This $465,752 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research at the University of Michigan-Dearborn to evaluate changes in cell chirality and cell-cell interactions within the neurovascular unit following traumatic brain injury (TBI). The key objectives are to determine the impacts of TBI on the chirality,...
This federal Project Grant award for $102,948.00, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research on the relationship between traumatic brain injury (TBI), hematopoietic stem cell (HSC) dysfunction, chronic neurodegeneration, and Alzheimer's disease (AD). The key objectives are to investigate how acute TBI induces changes to HSCs that...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...
This R01 project grant, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $404,100 in funding to The General Hospital Corporation (doing business as Massachusetts General Hospital) to investigate the mechanisms of chronic blood-brain barrier dysfunction following traumatic brain injury (TBI). The research aims to identify an endothelial...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate the role of thalamic microglia in driving cognitive impairment after cortical injuries, with a focus on traumatic brain injury (TBI). The $556,661 award, effective from June 18, 2024 to May 31, 2029, will enable researchers at the University of Alabama at Birmingham...