This federal Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under CFDA program 93.865 Child Health and Human Development Extramural Research, will fund a multi-disciplinary research effort to uncover novel insights into endocervical mucus secretion. The primary goal is to understand how female sex hormones regulate the biophysical properties of endocervical mucus in order to inform the development of novel, non-hormonal therapeutics for...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $474,946 to develop a novel, non-hormonal, female-initiated contraceptive device. The research aims to create a dual-compartment vaginal device that enables women to self-administer a bioresponsive polymer fiber mat and a supplemental fluid to fortify natural contraceptive barriers at the...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to elucidate the cellular and molecular mechanisms by which uterine epithelial estrogen receptor alpha (ERA) regulates the uterine immune environment during early pregnancy. The $641,750 award to the University of Georgia Research Foundation will fund a 2-year study using a mouse model to...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $1,963,122 to the University of Missouri System to conduct research on the molecular mechanisms regulating uterine development. The research aims to define critical physiological and genetic pathways that regulate uterine development, function, and regeneration in order to diagnose, treat, and prevent...
This Project Grant award, totaling $584,074, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award will fund research at the University of Massachusetts Medical School (UMass Medical) to investigate the role of ion channels, specifically L-type Ca2+ channels Cav1.2 and Cav1.3, in regulating uterine contraction and peristalsis, and their contribution to conditions...
The University of Georgia Research Foundation, Inc. (UGA Research Foundation) was awarded a $718,499 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, which runs from May 6, 2025 to April 30, 2030, supports research using 2D and 3D human pluripotent stem cell-derived adrenal gland tissue models to investigate adrenal gland development, disorders, and...
This Project Grant award, totaling $752,491, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research at Kent State University and Colorado State University to investigate the neural circuits and mechanisms mediating pulsatile and surge secretion of gonadotropin-releasing hormone (GnRH), which is critical for regulating fertility in female mammals. The...
This Project Grant award of $1,040,056 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to elucidate the role of leukocytes and their derived cytokines in the ovulatory process in humans. The study aims to characterize the expression profile of these cytokines and their receptors in dominant follicles throughout the ovulatory period, and to determine the impact of...
The University of Illinois has received a $655,014 Project Grant award from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant will fund research to determine if glycogen stores in the uterine endometrium are necessary for successful pregnancy. The project aims to 1) knockout glycogen synthase in the uterus of mice to assess the impact on fertility and pregnancy, and 2) elucidate the...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding a $1,255,424 research project titled "Efficacy Testing of a Multi-Level Family Planning Intervention to Increase Contraceptive Use and Reduce Unintended Pregnancy in Low Resource Settings." The overarching goal is to implement and evaluate a community-based intervention that...