Project Grant R01HD115770

Award Date 5/20/25
Completion Date 2/28/30
Dollars Obligated $743K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Portland, OR 97239, USA
Similar Awards
The National Institute of Child Health and Human Development (NICHD) awarded a $474,946 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Health Sciences and Pharmacy in St. Louis to develop a novel, female-initiated, non-hormonal contraceptive device. The project aims to create a multipurpose vaginal delivery system that combines a bioresponsive polymer fiber mat and an acid-buffering, mucoadhesive gel to fortify natural...
This $154,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to identify and characterize long non-coding RNAs (lncRNAs) that are regulated during the ovulatory process in mouse granulosa cells. The primary goal is to identify the top 5 most highly LH/HCG-regulated lncRNA candidates and investigate their functional role in the ovulatory...
The National Institute of Child Health and Human Development (NICHD) awarded a $232,308 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Magee-Womens Research Institute and Foundation in Pittsburgh, PA. The grant will fund research to elucidate the role of the hyaluronan matrices in establishing and maintaining the ovarian reserve and reproductive longevity, with a focus on understanding the ovarian stromal microenvironment across the...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to develop a bioadhesive vaginal film that can provide extended release of contraceptive and antiviral monoclonal antibodies. The $518,754 award, with a performance period from February 1, 2025 to January 31, 2026, will fund research by the Magee-Womens Research Institute and Foundation, with sub-awards to...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $2,018,716 to the University of Georgia Research Foundation to conduct research on the mechanisms of uterine fluid absorption during early pregnancy. The research aims to investigate the hormonal and ionic regulation of uterine fluid movement, with a focus on understanding how disruption of ion and water channels in the...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate dysregulation of uterine fluid movement as a potential mechanism for hormonal contraception. The $151,000 award to the University of Georgia Research Foundation will fund a 2-year project to determine the time-course effects of the contraceptive drug RU486 on uterine fluid...
This $584,074 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to investigate the roles of the ion channel subunits Cav1.2 and Cav1.3 in uterine smooth muscle cell function, uterine peristalsis, and their relationship to fertility and the uterine disease adenomyosis. The research aims to provide a fundamental understanding of uterine peristalsis...
This Project Grant award, funded by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research focused on understanding the molecular mechanisms regulating uterine development. The $1,963,122 award to the University of Missouri System will be used to conduct a collaborative research project with the central hypotheses that: (1) genetic and epigenetic mechanisms govern epithelial...
The National Institute of Child Health and Human Development (NICHD) awarded a $701,720 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The grant will support a 5-year research project to elucidate the effects of vaginal polyamines on immune responses, oxidative balance, and cervical remodeling in the context of...
The National Institute of Child Health and Human Development (NICHD) awarded a $147,486 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Trustees of the University of Pennsylvania. The grant, with a project period from September 1, 2025 to August 31, 2028, will fund research to investigate the role of the protein KIF2C in regulating the microtubule cytoskeleton during the oocyte-to-embryo transition. Key objectives include determining...

This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is providing $743,287 to Oregon Health & Science University (OHSU) to conduct a multi-disciplinary research study on endocervical mucus secretion. The goal is to uncover the cellular and pathway mechanisms that regulate mucus properties in response to hormonal changes, with the long-term aim of informing the development of novel, non-hormonal therapeutics for contraception or fertility enhancement. The project leverages OHSU's expertise in reproductive health, epithelial cell biology, mucus biophysics, and next-generation sequencing to combine clinical trials and in vitro models. By integrating these complementary approaches, the research team expects to discover and validate novel mechanisms underlying the regulation of endocervical mucus during the menstrual cycle, providing a scientific basis for utilizing mucus as a tool to control fertility. The award period runs from May 2025 to February 2030.

Generated 6/17/25, 4:09 AM